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High-Molecular-Weight Kininogen protein

Known as: Kininogen, High-Molecular-Weight [Chemical/Ingredient], Fitzgerald Factor, Kininogen.high molecular weight 
A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (2)

HKa protein, humanHigh molecular weight kininogen deficiency
In BloodKNG1 geneKininogen-1, humanProcess of secretion

Broader (1)

Kininogens

Papers overview

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2001
2001
Meta-activated nucleophilic aromatic substitution reaction: poly(biphenylene oxide)s with trifluoromethyl pendent groups via nitro displacement.
An aromatic ether linkage is found in many natural and synthetic products including poly(arylene ether)s, one of important high… 
Highly Cited
1995
Highly Cited
1995
High-molecular-weight kininogen is exclusively membrane bound on endothelial cells to influence activation of vascular endothelium.
An important biologic function of high-molecular-weight kininogen (HK) is to deliver bradykinin (BK) to its cellular receptors… 
Highly Cited
1993
Highly Cited
1993
Effect of microbial and mite proteases on low and high molecular weight kininogens. Generation of kinin and inactivation of thiol protease inhibitory activity.
Highly Cited
1990
Highly Cited
1990
Interactions of human mast cell tryptase with biological protease inhibitors.
Highly Cited
1989
Highly Cited
1989
Identification of plasma proteins adsorbed to hemodialyzers during clinical use.
An investigation has been made of the protein layers formed on hemodialysis membranes during clinical use. Dialyzers having… 
Highly Cited
1983
Highly Cited
1983
Inactivation of human high molecular weight kininogen by human mast cell tryptase.
Tryptase, the major neutral protease of human pulmonary mast cell secretory granules, rapidly inactivates human high m.w… 
Highly Cited
1981
Highly Cited
1981
Molecular weight and stoichiometry of the sodium- and potassium-activated adenosine triphosphatase subunits.
Highly Cited
1980
Highly Cited
1980
Radioimmunoassay of human high molecular weight kininogen in normal and deficient plasmas.
An RIA for human HMW kininogen, capable of detecting 150 pg of antigen, has been developed. Antibody to HMW kininogen was… 
Highly Cited
1979
Highly Cited
1979
Studies on human kininogens. I. Isolation, characterization, and cleavage by plasma kallikrein of high molecular weight (HMW)-kininogen.
1. Human high molecular weight (HMW)-kininogen was highly purified from human plasma by chromatographies on QAE-Sephadex A-50 and… 
Highly Cited
1969
Highly Cited
1969
Molecular weight studies on human plasminogen and plasmin at the microgram level.
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