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International consensus report on the investigation and management of primary immune thrombocytopenia.
This consensus document aims to report on new data and provide consensus-based recommendations relating to diagnosis and treatment of ITP in adults, in children, and during pregnancy.
Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.
An International Working Group of recognized expert clinicians convened a 2-day structured meeting to define standard terminology and definitions for primary ITP and its different phases and criteria for the grading of severity, and clinically meaningful outcomes and response.
Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology.
This report begins with a brief summary of the panel’s recommendations, followed by a more detailed analysis of its methodology, the findings of the comprehensive literature review, and a full presentation of the recommendations.
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane that lines the circulatory system with its primary essential function being the maintenance of vessel wall permeability.…
Immune thrombocytopenic purpura.
The authors of this up-to-date review discuss the current understanding of pathophysiology and, in particular, the way in which autoantibodies against platelets are generated.
American Society of Hematology 2019 guidelines for immune thrombocytopenia.
There was a lack of evidence to support strong recommendations for various management approaches, and a large focus was placed on shared decision-making, especially with regard to second-line therapy.
The ITP syndrome: pathogenic and clinical diversity.
It is suggested that primary ITP is also best thought of as an autoimmune syndrome and better understanding of pathogenesis and tolerance checkpoint defects leading to autoantibody formation may facilitate patient-specific approaches to diagnosis and management.
SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia
The coronavirus disease 2019 (Covid-19) pandemic caused by severe acute respiratory syndrome coronav virus 2 (SARS-CoV-2) stimulated the development of highly effective vaccines that were produced with unprecedented speed with the use of diverse technologies, and certain findings were consistent across the three studies.
American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia.
These evidence-based guidelines of the American Society of Hematology are intended to support patients, clinicians, and other health care professionals in their decisions about diagnosis and management of HIT.
How I treat idiopathic thrombocytopenic purpura (ITP).
Our goal is to set forth our opinion of the best approach to managing adults with primary idiopathic (autoimmune) thrombocytopenic purpura (ITP), with emphasis on the word “opinion.” The paucity of…