Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH
- M. Cattaneo, C. Cerletti, A. Michelson
- MedicineJournal of Thrombosis and Haemostasis
- 1 June 2013
The Platelet Physiology Subcommittee of the Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis formed a working party of experts with the aim of producing a series of consensus recommendations for standardizing LTA, which formed the basis of a consensus document, which is the subject of the present report.
Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products*♦
- M. Wada, C. DeLong, W. Smith
- Biology, Environmental ScienceJournal of Biological Chemistry
- 3 August 2007
In vitro specificities of prostanoid enzymes and receptors toward EPA-derived, 3-series versus AA- derived, 2-series prostanoids substrates and products are reported and biochemical data predict that increasing phospholipid EPA/AA ratios in cells would dampen prostanoidal signaling.
Use of factor IX complex in warfarin-related intracranial hemorrhage.
- N. Boulis, M. Bobek, A. Schmaier, J. Hoff
- MedicineNeurosurgery
- 1 November 1999
The use of FIXCC accelerated correction of warfarin-related anticoagulation in the presence of intracranial hemorrhage is linked to better neurological outcomes and a higher complication rate for the FFP-treated group.
Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes.
- R. Colman, A. Schmaier
- MedicineBlood
- 15 November 1997
THE KALLIKREIN-KININ system was first recognized as a plasma and tissue proteolytic system responsible for the liberation of the vasoactive, proinflammatory mediator, bradykinin (BK).[1][1] BK, a…
The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities
- A. Schmaier
- Medicine, BiologyJournal of Thrombosis and Haemostasis
- 1 January 2016
There is revived interest in the CAS and KKS due to better understanding of their activities and the new appreciation of these systems will lead to several new therapies for a variety of medical disorders.
Identification and Characterization of Prolylcarboxypeptidase as an Endothelial Cell Prekallikrein Activator*
- Z. Shariat-Madar, F. Mahdi, A. Schmaier
- Biology, ChemistryJournal of Biological Chemistry
- 17 May 2002
PKA did not correct the coagulant defect in factor XI deficient plasma, was purified from HUVEC cultured in factor XII-deficient serum, was not detected by antibody to factor XII, did not activate FXI, and was not inhibited by a neutralizing antibody to FXII.
In vivo roles of factor XII.
- T. Renné, A. Schmaier, K. Nickel, M. Blombäck, C. Maas
- Biology, MedicineBlood
- 19 November 2010
The goal of this review is to summarize the in vivo functions of FXII, with special focus to its functions in thrombosis and vascular biology.
The elusive physiologic role of Factor XII.
- A. Schmaier
- Biology, MedicineJournal of Clinical Investigation
- 2 September 2008
A novel biologic surface for FXII activation and activity is described, which initiates inflammatory events independent of hemostasis, which is described in this issue of the JCI.
SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy
- M. Chung, S. Karnik, L. Svensson
- Medicine, BiologyEBioMedicine
- 1 August 2020
Assembly and activation of the plasma kallikrein/kinin system: a new interpretation.
- Z. Shariat-Madar, F. Mahdi, A. Schmaier
- BiologyInternational Immunopharmacology
- 1 December 2002
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