Heparin Cofactor II

Known as: Protease Inhibitor Leuserpin 2, Leuserpin 2, HLS2 
A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
The mucopolysaccharidoses are a group of lysosomal storage disorders caused by defects in the degradation of glycosaminoglycans… (More)
  • table 1
  • figure 5
Is this relevant?
Review
2007
Review
2007
Heparin cofactor II (HCII) has several biochemical properties that distinguish it from other serpins: (1) it specifically… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2007
2007
Heparin cofactor II (HCII) is a plasma protein that inhibits thrombin when bound to dermatan sulfate or heparin. HCII-deficient… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2004
2004
Thrombin (T) inactivation by the serpin, heparin cofactor II (HCII), is accelerated by the glycosaminoglycans (GAGs) dermatan… (More)
Is this relevant?
2003
2003
The effects of bivalent cations on heparin binding, structure, and thrombin inhibition rates of heparin cofactor II were examined… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The serine proteases sequentially activated to form a fibrin clot are inhibited primarily by members of the serpin family, which… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
1996
1996
Heparin cofactor II (HCII) is a serine proteinase inhibitor in human plasma that rapidly inhibits thrombin in the presence of… (More)
Is this relevant?
1993
1993
Two small interstitial dermatan sulfate-containing proteoglycans, biglycan and decorin, are present in extracellular matrices of… (More)
Is this relevant?
1985
1985
Heparin cofactor II (HC II) is a heparin-dependent inhibitor of thrombin, distinct from antithrombin III (AT III). This study was… (More)
Is this relevant?
1985
1985
Human heparin cofactor II is a plasma protein that is known to inhibit thrombin. The rate of thrombin inhibition by heparin… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?