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Heat Shock Protein HSP 90-Beta

Known as: HSPCB, HSP90AB1, HSP 84 
Heat shock protein HSP 90-beta (724 aa, ~83 kDa) is encoded by the human HSP90AB1 gene. This protein plays a role in the modulation of both… 
National Institutes of Health

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Cytoplasmic matrixHSP90 Heat-Shock ProteinsHSP90AB1 geneHSP90AB1 wt Allele

Papers overview

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2011
2011
Anti-HSP 90 autoantibodies in sera of infertile women identify a dominant , conserved epitope EP 6 ( 380-389 ) of HSP 90 beta protein
Background: We earlier reported a simple specific test for detection of anti-ovarian antibodies in infertile women and identified… 
2011
2011
IN SILICO DRUG DESIGNING APPROACHES FOR LATENT AUTOIMMUNE DIABETES IN ADULTS (LADA)
Autoantibody positivity together with subsequent development of insulin deficiency led to the introduction of latent autoimmune… 
2010
2010
Hsp 90 interaction with INrf 2 ( Keap 1 ) mediates stress-induced Nrf 2 activation
INrf2(Keap1) functions as an adapter for Cul3/Rbx1-mediated degradation of Nrf2. In response to stress, Nrf2 is released from… 
Review
2007
Review
2007
Inhibition of Hsp 90 : AMultitarget Approach to Radiosensitization
Hsp90, the 90 kDaheat shock protein, is a highly expressedmolecular chaperone that modulates the stability and/or transport of a… 
2005
2005
ArticleHDAC 6 Regulates Hsp 90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor
Jeffrey J. Kovacs,1 Patrick J.M. Murphy,3 Stéphanie Gaillard,1 Xuan Zhao,1 June-Tai Wu,1 Christopher V. Nicchitta,2 Minoru… 
2004
2004
3 D structure of human FK 506-binding protein 52 : Implications for the assembly of the glucocorticoid receptor Hsp 90 immunophilin heterocomplex
FK506-binding protein 52 (FKBP52), which binds FK506 and possesses peptidylprolyl isomerase activity, is an important… 
2003
2003
Synergistic Activation of eNOS by HSP 90 and Akt : Calcium-independent Endothelial Nitric Oxide Synthase Activation by Insulin Involves Formation of an HSP 90-Akt-eNOS Complex
Endothelial nitric oxide synthase (eNOS), which generates the endogenous vasodilator, nitric oxide (NO), is highly regulated by… 
2002
2002
Ligand discrimination by TPR domains : Relevance and selectivity of EEVD-recognition in Hsp 70-Hop-Hsp 90 complexes RUNNING TITLE : PEPTIDE RECOGNITION MOTIFS OF HOP TPR DOMAINS
* Department of Cellular Biochemistry, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18A, D-82152 Martinsried, Germany… 
2000
2000
Hsp 90 Regulates p 50 cdc 37 Function during the Biogenesis of the Active Conformation of the Heme-regulated eIF 2 a Kinase *
Recent studies indicate that p50 facilitates Hsp90mediated biogenesis of certain protein kinases. In this report, we examined… 
1997
1997
This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected on April 29 , 1997 . In vivo functions of the Saccharomyces cerevisiae Hsp…
In the highly concentrated environment of the cell, polypeptide chains are prone to aggregation during synthesis (as nascent…