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Heat Shock 70 kDa Protein 1A/1B

Known as: HSP72, Heat Shock 70 kDa Protein 1/2, HSP70.1/HSP70.2 
Heat shock 70 kDa protein 1A/1B (641 aa, ~70 kDa) is encoded by the human HSPA1A and HSPA1B genes. This protein is involved in the mediation of… 
National Institutes of Health

Related topics

Related topics

17 relations
Cell Growth RegulationCytoplasmEndoplasmic ReticulumHSPA1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Dual Role of Heat Shock Proteins as Regulators of Apoptosis and Innate Immunity
Stress or heat shock proteins (HSPs) 70 and 90 are powerful chaperones whose expression is induced in response to a wide variety… 
Highly Cited
2008
Highly Cited
2008
Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.
Review
2008
Review
2008
Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury.
Highly Cited
2004
Highly Cited
2004
Inhibition of Hsp72-mediated protein refolding by 4-hydroxy-2-nonenal.
A proteomic approach was applied to liver cytosol from rats fed a diet consisting of high fat and ethanol to identify 4-hydroxy-2… 
Highly Cited
2003
Highly Cited
2003
Role of extracellular HSP72 in acute stress-induced potentiation of innate immunity in active rats.
Acute stress can compromise acquired, and potentiate innate, immunity. Recent evidence suggests that the impact of stress on… 
Highly Cited
2003
Highly Cited
2003
Habitual physical activity facilitates stress-induced HSP72 induction in brain, peripheral, and immune tissues.
The mechanism(s) for how physically active organisms are resistant to many damaging effects of acute stressor exposure is unknown… 
Highly Cited
2002
Highly Cited
2002
Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis
ABSTRACT The major inducible heat shock protein Hsp72 has been shown to protect cells from certain apoptotic stimuli. Here we… 
Highly Cited
2001
Highly Cited
2001
Exercise increases serum Hsp72 in humans
Abstract Recent evidence suggests that heat shock proteins (Hsps) may have an important systemic role as a signal to activate the… 
Highly Cited
1995
Highly Cited
1995
A stress‐inducible 72‐kDa heat‐shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells
It is suggested that members of the heat‐shock protein (HSP) 70 and 90 families are involved in intracellular antigen processing… 
Highly Cited
1992
Highly Cited
1992
Heat Shock Protein Induction in Rat Hearts: A Role for Improved Myocardial Salvage After Ischemia and Reperfusion?
BackgroundTo test the hypothesis that the heat shock response is associated with improved myocardial salvage after myocardial… 
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