Half Maximal Inhibitory Concentration Subject Result Measurement

Known as: IC50 Subject Result, IC50 Treatment Result, IC50S 
A measurement of titer of a viral organism or biological/biochemical reaction that has been exposed to a concentration of a specific drug expected to… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
In Papua, Indonesia, the antimalarial susceptibility of Plasmodium vivax (n = 216) and P. falciparum (n = 277) was assessed using… (More)
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Highly Cited
2007
Highly Cited
2007
New therapeutic agents for the treatment of malaria, the world's most deadly parasitic disease, are urgently needed. Malaria… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the DNA gyrase GyrA2GyrB2 complex are associated with resistance to quinolones in Mycobacterium tuberculosis. As… (More)
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Highly Cited
2005
Highly Cited
2005
Artemisinin derivatives are an essential component of treatment against multidrug-resistant Plasmodium falciparum malaria. We… (More)
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Highly Cited
2003
Highly Cited
2003
Vinflunine is a novel fluorinated Vinca alkaloid currently in Phase II clinical trials, which in preclinical studies exhibited… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 (COX-2) is an important cellular target for both therapy and/or prevention of inflammatory disorders and cancer… (More)
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Highly Cited
1999
Highly Cited
1999
Many P-glycoprotein (P-gp) inhibitors studied in vitro and in vivo are also known or suspected to be substrates and/or inhibitors… (More)
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Highly Cited
1998
Highly Cited
1998
Metallic biomaterials are generally used for replacement of structural components of the human body such as bones, joints, and… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Cardiovascular instability after intravenous induction of anesthesia may be explained partly by direct negative… (More)
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Highly Cited
1987
Highly Cited
1987
The influence of endogenous and exogenous acidic amino acids on the binding of [3H]-MK-801, a selective, non-competitive… (More)
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