Inhibitory Concentration 50

Known as: Concentration 50, Inhibitory, IC50, inhibitory concentration 50% (IC50) 
The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Purpose: Oxidative stress has been shown to play an important role in the development of anaemia in malaria. Indeed, increase in… (More)
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Highly Cited
2006
Highly Cited
2006
In present study, we carried out a systematic record of the relative antioxidant activity in selected Iranian medicinal plant… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Vascular calcification is the most prominent underlying pathological finding in patients with uraemia, and is a… (More)
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Highly Cited
2000
Highly Cited
2000
The aim of this study was to identify whey-derived peptides with angiotensin I-converting enzyme (ACE) inhibitory activity. The… (More)
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Highly Cited
1996
Highly Cited
1996
Sildenafil (Viagra, UK-92,480) is a novel oral agent under development for the treatment of penile erectile dysfunction. Erection… (More)
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Highly Cited
1996
Highly Cited
1996
Inflammatory processes in chronic rejection remain a serious clinical problem in organ transplantation. Activated cellular… (More)
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Highly Cited
1995
Highly Cited
1995
PD 098059 has been shown previously to inhibit the dephosphorylated form of mitogen-activated protein kinase kinase-1 (MAPKK1… (More)
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Highly Cited
1994
Highly Cited
1994
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor… (More)
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Highly Cited
1991
Highly Cited
1991
Staurosporine is the most potent inhibitor of protein kinase C (PKC) described in the literature with a half-maximal inhibitory… (More)
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Highly Cited
1991
Highly Cited
1991
Topical application of curcumin, the yellow pigment in turmeric and curry, strongly inhibited 12-O-tetradecanoylphorbol-13… (More)
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