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HTR2C gene

Known as: SEROTONIN 5-HT-1C RECEPTOR, FORMERLY, 5-HT2C, SEROTONIN 5-HT-2C RECEPTOR 
This gene is involved in neurotransmitter-dependent G protein-coupled receptor signaling.
National Institutes of Health

Related topics

Related topics

11 relations
5-Hydroxytryptamine Receptor 2C, humanCalcium SignalingG Protein-Coupled Receptor SignalingHTR1B gene
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample.
BACKGROUND Drug-induced bodyweight gain (BWG) is a serious concern in pharmacotherapy with second-generation antipsychotics. The… Expand
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Highly Cited
2010
Highly Cited
2010
Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.
AIMS This study aims to test for possible associations between the gene coding for the 5-HT2C receptor and antipsychotic-induced… Expand
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Highly Cited
2009
Highly Cited
2009
Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour.
The Prader-Willi syndrome (PWS) genetic interval contains several brain-expressed small nucleolar (sno)RNA species that are… Expand
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Highly Cited
2009
Highly Cited
2009
Association Between HTR2C and HTR2A Polymorphisms and Metabolic Abnormalities in Patients Treated With Olanzapine or Clozapine
Serotonin 2C and 2A receptor (5-HT2C and 5-HT2A) antagonisms are hypothesized to play a role in the metabolic adverse effects… Expand
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Highly Cited
2009
Highly Cited
2009
HTR2C Gene Polymorphisms and the Metabolic Syndrome in Patients With Schizophrenia: A Replication Study
In a previous study, we found an association between 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C) polymorphisms and the… Expand
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Review
2008
Review
2008
Serotonin receptors.
2. Classification of Serotonin Receptors 1625 2.1. Gq/11-Coupled Receptor Types 1626 2.1.1. The 5-HT2A Receptor 1626 2.1.2. The 5… Expand
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Highly Cited
2007
Highly Cited
2007
Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis.
The 5-HT2C receptor has been hypothesized to represent an important modulator in feeding behaviour. Evidence was based on the… Expand
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Highly Cited
2007
Highly Cited
2007
The Association Between HTR2C Gene Polymorphisms and the Metabolic Syndrome in Patients With Schizophrenia
The use of antipsychotics is associated with metabolic side effects, which put patients with schizophrenia or related disorders… Expand
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Highly Cited
2007
Highly Cited
2007
HTR2C and HTR1A gene variants in German and Italian suicide attempters and completers.
The serotonin 2C (HTR2C) and 1A (HTR1A) receptors have been involved in suicide-related behaviors. We studied gene variants of… Expand
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Highly Cited
2004
Highly Cited
2004
A 5-HT2C receptor promoter polymorphism (HTR2C - 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes.
The serotonin 5-HT(2C) receptor (HTR2C) helps regulate appetite and body weight. An HTR2C promoter polymorphism (-759C/T) has… Expand
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