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HSPB8 wt Allele

Known as: CMT2L, Heat Shock 27kDa Protein 8 Gene, HSP22 
Human HSPB8 wild-type allele is located in the vicinity of 12q24.23 and is approximately 16 kb in length. This allele, which encodes heat shock… 
National Institutes of Health

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AutophagyCharcot-Marie-Tooth disease, Type 2IHeat Shock Protein Beta-8cellular response to unfolded protein

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HSPB8 gene

Papers overview

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2008
2008
Phosphorylation by cyclic AMP-dependent protein kinase inhibits chaperone-like activity of human HSP22 in vitro
Human small heat shock protein with molecular mass 22 kD (HSP22, HspB8) contains two Ser residues (Ser24 and Ser57) in consensus… 
2007
2007
Effect of mutations in the beta5-beta7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11).
The human genome encodes ten different small heat shock proteins, each of which contains the so-called alpha-crystallin domain… 
Highly Cited
2006
Highly Cited
2006
Small heat shock protein HspB8: its distribution in Alzheimer's disease brains and its inhibition of amyloid-beta protein aggregation and cerebrovascular amyloid-beta toxicity.
Alzheimer's disease (AD) is characterized by pathological lesions, such as senile plaques (SPs) and cerebral amyloid angiopathy… 
2006
2006
Regulation of Sam68 activity by small heat shock protein 22
Sam68 associates with c‐Src kinase during mitosis. We previously demonstrated that Sam68 functionally replaces and/or synergizes… 
Highly Cited
2004
Highly Cited
2004
Interaction of Human HSP22 (HSPB8) with Other Small Heat Shock Proteins*
Mammalian small heat shock proteins (sHSP) are abundant in muscles and are implicated in both muscle function and myopathies… 
2004
2004
Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster
Highly Cited
2001
Highly Cited
2001
In Vivo Modifications of the Maize Mitochondrial Small Heat Stress Protein, HSP22*
A maize (Zea mays L.) small heat shock protein (HSP), HSP22, was previously shown to accumulate to high levels in mitochondria… 
Highly Cited
1997
Highly Cited
1997
Cell-specific expression and heat-shock induction of Hsps during spermatogenesis in Drosophila melanogaster.
The developmental and heat-shock-induced expression of two small heat-shock proteins (Hsp23 and Hsp27) was investigated during… 
1996
1996
Investigation of damping effects on statistical energy analysis of coupled structures
Abstract The effects of damping on energy sharing in coupled systems are investigated. The approach taken is to compute the… 
1994
1994
The Drosophila broad-complex regulates developmental changes in transcription and chromatin structure of the 67B heat-shock gene cluster.
At the end of the third larval instar of Drosophila, ecdysone triggers the tissue-specific activation of gene expression. In… 
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