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HSPB8 gene

Known as: Heat Shock 22kDa Protein 8 Gene, HEAT-SHOCK 27-KD PROTEIN 8, CMT2L 
This gene plays a role in both protein folding and autophagy.
National Institutes of Health

Related topics

Related topics

6 relations
AutophagyHeat Shock Protein Beta-8cellular response to unfolded proteinintracellular protein transport

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HSPB8 wt Allele

Papers overview

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Highly Cited
2016
Highly Cited
2016
Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy
Objective: To report novel disease and pathology due to HSPB8 mutations in 2 families with autosomal dominant distal… 
Highly Cited
2009
Highly Cited
2009
Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction.
The molecular chaperone HspB8 [Hsp (heat-shock protein) B8] is member of the B-group of Hsps. These proteins bind to unfolded or… 
Highly Cited
2006
Highly Cited
2006
Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis1
Dendritic cells (DCs) are specialized APCs that can be activated upon pathogen recognition as well as recognition of endogenous… 
Highly Cited
2005
Highly Cited
2005
HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.
The family of small heat shock proteins (sHsp) is composed of 10 members in mammals, four of which are found mutated in diseases… 
Highly Cited
2005
Highly Cited
2005
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L
Charcot-Marie-Tooth (CMT) disease is the most common inherited motor and sensory neuropathy. We have previously described a large… 
Highly Cited
2005
Highly Cited
2005
H9, H10, and H11 compose a cluster of Hessian fly-resistance genes in the distal gene-rich region of wheat chromosome 1AS
H9, H10, and H11 are major dominant resistance genes in wheat, expressing antibiosis against Hessian fly [(Hf) Mayetiola… 
Highly Cited
2004
Highly Cited
2004
Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity.
A newly identified 22 kDa protein that interacts with Hsp27 (heat-shock protein 27) was shown to possess the characteristic alpha… 
Highly Cited
2004
Highly Cited
2004
Interaction of Human HSP22 (HSPB8) with Other Small Heat Shock Proteins*
Mammalian small heat shock proteins (sHSP) are abundant in muscles and are implicated in both muscle function and myopathies… 
Highly Cited
1995
Highly Cited
1995
Sequence and expression of the mRNA encoding HSP22, the mitochondrial small heat-shock protein in pea leaves.
A 3 h treatment at 40 degrees C of pea (Pisum sativum var. Douce Provence) plants induces production and accumulation of a small… 
Highly Cited
1986
Highly Cited
1986
Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22
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