cellular response to unfolded protein

Known as: Protein Responses, Unfolded, Responses, Unfolded Protein, Response, Unfolded Protein 
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the… (More)

Topic mentions per year

Topic mentions per year

1973-2017
020040019732017

Papers overview

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Review
2016
Review
2016
The endoplasmic reticulum (ER) is a critical organelle for normal cell function and homeostasis. Disturbance in the protein… (More)
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Review
2016
Review
2016
Unfolded protein responses (UPR), consisting of three major transducers PERK, IRE1, and ATF6, occur in the midst of a variety of… (More)
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Highly Cited
2006
Highly Cited
2006
The protein folding capacity of the endoplasmic reticulum (ER) is regulated by the unfolded protein response (UPR). The UPR… (More)
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Highly Cited
2003
Highly Cited
2003
The mammalian unfolded protein response (UPR) protects the cell against the stress of misfolded proteins in the endoplasmic… (More)
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Highly Cited
2003
Highly Cited
2003
The transcription factor X-box binding protein 1 (XBP-1) is essential for the differentiation of plasma cells and the unfolded… (More)
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Highly Cited
2001
Highly Cited
2001
In yeast, the transmembrane protein kinase/endoribonuclease Ire1p activated by endoplasmic reticulum stress cleaves HAC1 mRNA… (More)
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Highly Cited
2000
Highly Cited
2000
The unfolded protein response (UPR) regulates gene expression in response to stress in the endoplasmic reticulum (ER). We… (More)
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Highly Cited
1999
Highly Cited
1999
The unfolded protein response (UPR) controls the levels of molecular chaperones and enzymes involved in protein folding in the… (More)
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Highly Cited
1997
Highly Cited
1997
The endoplasmic reticulum (ER) communicates with the nucleus through the unfolded protein response (UPR), which senses… (More)
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Highly Cited
1996
Highly Cited
1996
Cells respond to an accumulation of unfolded proteins in the endoplasmic reticulum (ER) by increasing transcription of genes… (More)
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