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cellular response to unfolded protein
Known as:
Protein Responses, Unfolded
, Responses, Unfolded Protein
, Response, Unfolded Protein
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A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the…
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National Institutes of Health
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Related topics
Related topics
49 relations
C1GALT1C1 gene
C1GALT1C1 wt Allele
CANX gene
CDC37 gene
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Narrower (1)
endoplasmic reticulum unfolded protein response
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine.
C. Gajate
,
F. Mollinedo
Anti-Cancer Agents in Medicinal Chemistry
2014
Corpus ID: 4488075
The so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor compounds that target cell membranes…
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Review
2008
Review
2008
Endoplasmic reticulum stress in the kidney
M. Kitamura
Clinical and Experimental Nephrology
2008
Corpus ID: 195318218
Endoplasmic reticulum (ER) stress is involved in a wide range of pathological circumstances including neurodegenerative disorders…
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Highly Cited
2008
Highly Cited
2008
Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-κB and ATF4
T. Rzymski
,
A. Paantjens
,
J. Bod
,
Adrian L. Harris
Oncogene
2008
Corpus ID: 1751760
Under anoxia a coordinated, cytoprotective program is induced, called the unfolded protein response (UPR). Activating…
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2008
2008
Ricin Inhibits Activation of the Unfolded Protein Response by Preventing Splicing of the HAC1 mRNA*
Bijal A. Parikh
,
Andrew Tortora
,
Xiao-Ping Li
,
N. Tumer
Journal of Biological Chemistry
2008
Corpus ID: 11303256
Ricin A chain (RTA) inhibits protein synthesis by removing a specific adenine from the highly conserved α-sarcin/ricin loop in…
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Highly Cited
2007
Highly Cited
2007
Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.
Teresa Nieto-Miguel
,
R. Fonteriz
,
Laura Vay
,
C. Gajate
,
S. López-Hernández
,
F. Mollinedo
Cancer Research
2007
Corpus ID: 13380729
The endoplasmic reticulum (ER) has been posited as a potential anticancer target. The synthetic antitumor alkyl-lysophospholipid…
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Highly Cited
2006
Highly Cited
2006
AtUTr1, a UDP-glucose/UDP-galactose Transporter from Arabidopsis thaliana, Is Located in the Endoplasmic Reticulum and Up-regulated by the Unfolded Protein Response*
Francisca C. Reyes
,
Lorena Marchant
,
L. Norambuena
,
Ricardo Nilo
,
H. Silva
,
A. Orellana
Journal of Biological Chemistry
2006
Corpus ID: 22329550
The folding of glycoproteins in the endoplasmic reticulum (ER) depends on a quality control mechanism mediated by the calnexin…
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Highly Cited
2005
Highly Cited
2005
Rapid B Cell Receptor-induced Unfolded Protein Response in Nonsecretory B Cells Correlates with Pro- Versus Antiapoptotic Cell Fate*
Alison H. Skalet
,
J. Isler
,
L. King
,
H. Harding
,
D. Ron
,
J. Monroe
Journal of Biological Chemistry
2005
Corpus ID: 24022200
The adaptive unfolded protein response (UPR) is essential for the development of antibody-secreting plasma cells. B cells induced…
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Highly Cited
1997
Highly Cited
1997
Gene induction in response to unfolded protein in the endoplasmic reticulum is mediated through Ire1p kinase interaction with a transcriptional coactivator complex containing Ada5p.
A. Welihinda
,
W. Tirasophon
,
S. R. Green
,
R. Kaufman
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 2412892
In eukaryotic cells, accumulation of unfolded protein in the endoplasmic reticulum induces transcription of a family of genes…
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Highly Cited
1991
Highly Cited
1991
Molecular and supermolecular origins of enhanced electric conductivity in template-synthesized polyheterocyclic fibrils. 1. Supermolecular effects
Z. Cai
,
Junting Lei
,
W. Liang
,
V. Menon
,
C. Martin
1991
Corpus ID: 54192720
Abstract : The pores in a nanoporous membrane can be used as templates for the synthesis of nanostructures. We have recently…
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Highly Cited
1973
Highly Cited
1973
Biochemical basis of radiation-sensitivity in mutants of Neurospora crassa.
T. E. Worthy
,
J. Epler
Mutation research
1973
Corpus ID: 32186932
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