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Heat Shock Protein Beta-8

Known as: Protein Kinase H11, E2-Induced Gene 1 Protein, Small Stress Protein-Like Protein HSP22 
Heat shock protein beta-8 (196 aa, ~22 kDa) is encoded by the human HSPB8 gene. This protein plays a role in the regulation of autophagy and as a… 
National Institutes of Health

Related topics

Related topics

8 relations
AutophagyHSPB8 geneHSPB8 wt AlleleHeat shock proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons
Although autophagy has been proposed to play an emerging role in diabetic neuropathy, autophagy and its possible role remains… 
2016
2016
Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8
Charcot–Marie–Tooth (CMT) disease is an inherited peripheral neuromuscular disorder characterized by length-dependent and… 
2016
2016
Interaction of small heat shock proteins with light component of neurofilaments (NFL)
The interaction of human small heat shock protein HspB1, its point mutants associated with distal hereditary motor neuropathy… 
Highly Cited
2015
Highly Cited
2015
A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis
The co-chaperone BAG3, in complex with the heat shock protein HSPB8, plays a role in protein quality control during mechanical… 
Review
2014
Review
2014
The small heat shock protein HspB8: role in nervous system physiology and pathology.
The accumulation and aggregation of misfolded proteins can be highly cytotoxic and may underlie several human degenerative… 
2012
2012
The chaperone-like activity of rat HspB8/Hsp22 and dynamic molecular transition related to oligomeric architectures in vitro.
HspB8/Hsp22 is a functionally distinct small heat shock proteins (sHsp) and is preferentially expressed in brain, heart, skeletal… 
2011
2011
Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase
A number of phosphomimicking mutants (replacement of Ser/Thr residues by Asp) of human small heat shock protein HspB8 were… 
2010
2010
The pivotal role of the β7 strand in the intersubunit contacts of different human small heat shock proteins
Human αB-crystallin and small heat shock proteins HspB6 and HspB8 were mutated so that all endogenous Cys residues were replaced… 
2009
2009
Small heat shock proteins associated with cerebral amyloid angiopathy of hereditary cerebral hemorrhage with amyloidosis (Dutch type) induce interleukin-6 secretion
2007
2007
Antiestrogenic effect of paradichlorobenzene in immature mice and rats
A significant increase/decrease in uterine and ovarian weights was occasionally seen in immature mice and rats subcutaneously… 
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