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HOE-498

Known as: HOE 498, HOE498 
 
National Institutes of Health

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Highly Cited
1986
Highly Cited
1986
The effects of the angiotensin converting enzyme (ACE) inhibitors captopril, enalapril, HOE 498, and its prodrug on reperfusion… Expand
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1986
1986
The novel prodrug-converting-enzyme (CE) inhibitor perindopril (S9490-3) diacid was found to be as potent as ramipril (Hoe498… Expand
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1986
1986
The spontaneously hypertensive rat (SHR) has many characteristics indicative of an overactive brain-angiotensin system. Since… Expand
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Highly Cited
1985
Highly Cited
1985
Inhibition of angiotensin II generation in the plasma does not fully explain the antihypertensive effects of converting enzyme… Expand
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1985
1985
The role of converting enzyme (CE) in heart function was studied by assessing the inhibition of CE activity in rat heart tissue… Expand
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1985
1985
The effect of different oral doses of HOE 498, a new non-sulphydryl containing converting enzyme inhibitor, was investigated in a… Expand
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1985
1985
The effect of various doses of the new angiotensin-converting enzyme inhibitor HOE 498 was compared with that of placebo in… Expand
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1984
1984
The mechanism of antihypertensive action of converting enzyme (CE) inhibitors was studied by comparing two compounds of different… Expand
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1984
1984
SummaryThe pharmacokinetics and pharmacodynamics of the angiotensin converting enzyme inhibitor HOE 498 were investigated in 10… Expand
  • figure 2
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1984
1984
After oral administration, 2 mg/kg in rat and dog, 10 mg in man, of the carbon-14-labeled angiotensin I converting enzyme… Expand
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