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Ramipril

Known as: Ramipril [Chemical/Ingredient], (2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, Ramiprilum 
A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (3)

AltaceHOE-498ramiprilat
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Effect of angiotensin receptor blockade on systemic right ventricular function and size: a small, randomized, placebo-controlled study.
Highly Cited
2005
Highly Cited
2005
Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction.
Highly Cited
2003
Highly Cited
2003
Progression of renal insufficiency in type 2 diabetes with and without microalbuminuria: results of the Heart Outcomes and Prevention Evaluation (HOPE) randomized study.
Highly Cited
2002
Highly Cited
2002
From the HOPE to the ONTARGET and the TRANSCEND studies: challenges in improving prognosis.
Highly Cited
2001
Highly Cited
2001
Simultaneous determination of hydrochlorothiazide and several inhibitors of angiotensin-converting enzyme by capillary electrophoresis.
Highly Cited
2000
Highly Cited
2000
ACE inhibition in cardiovascular disease.
An important article in this issue of the Journal describes the results of the Heart Outcomes Prevention Evaluation (HOPE) study… 
Highly Cited
1997
Highly Cited
1997
Analysis of ACE inhibitors in pharmaceutical dosage forms by derivative UV spectroscopy and liquid chromatography (HPLC).
Highly Cited
1996
Highly Cited
1996
The HOPE (Heart Outcomes Prevention Evaluation) Study: the design of a large, simple randomized trial of an angiotensin-converting enzyme inhibitor (ramipril) and vitamin E in patients at high risk…
OBJECTIVE To describe the design of the HOPE (Heart Outcomes Prevention Evaluation) study. DESIGN Description of the key design… 
Highly Cited
1992
Highly Cited
1992
ACE-inhibition induces NO-formation in cultured bovine endothelial cells and protects isolated ischemic rat hearts.
Highly Cited
1986
Highly Cited
1986
Beneficial effects of the converting enzyme inhibitor, ramipril, in ischemic rat hearts.
Components of the renin-angiotensin system (RAS) have been found in heart tissue and it is likely that angiotensin II (ANG II) is… 
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