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Ramipril

Known as: Ramipril [Chemical/Ingredient], (2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, Ramiprilum 
A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de… 
National Institutes of Health

Related topics

Related topics

24 relations

Narrower (3)

AltaceHOE-498ramiprilat
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
The fixed-dose combination drug for secondary cardiovascular prevention project: improving equitable access and adherence to secondary cardiovascular prevention with a fixed-dose combination drug…
Review
2009
Review
2009
The sudden demise of dual renin-angiotensin system blockade or the soft science of the surrogate end point.
Highly Cited
2007
Highly Cited
2007
Neurohumoral effects of the new orally active renin inhibitor, aliskiren, in chronic heart failure
Review
2005
Review
2005
Cardiovascular risk in patients with mild renal insufficiency: implications for the use of ACE inhibitors.
Highly Cited
2001
Highly Cited
2001
Aminoguanidine and ramipril prevent diabetes-induced increases in protein kinase C activity in glomeruli, retina and mesenteric artery.
This study investigated the effects of insulin therapy, inhibition of advanced glycation end-product formation with… 
Highly Cited
2000
Highly Cited
2000
Increased apoptosis in the heart of genetic hypertension, associated with increased fibroblasts.
Highly Cited
1997
Highly Cited
1997
Ramipril prevents endothelial dysfunction induced by oxidized low-density lipoproteins: a bradykinin-dependent mechanism.
We wished to determine whether the acute toxic effects of oxidized LDL are attenuated in aortas isolated from rats chronically… 
Highly Cited
1996
Highly Cited
1996
Angiotensin-converting enzyme inhibition limits dysfunction in adjacent noninfarcted regions during left ventricular remodeling.
Review
1993
Review
1993
Contribution of bradykinin to the cardiovascular effects of ramipril.
From pharmacologic investigations and clinical studies it is known that angiotensin-converting enzyme (ACE) inhibitors exhibit… 
1992
1992
Role of Bradykinin in Chronic Antihypertensive Actions of Rarnipril in Different Hypertension Models
We investigated the chronic effect of bradykinin B2-receptor blockade on the antihypertensive actions of the angiotensin… 
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