Ramipril

Known as: Ramipril [Chemical/Ingredient], (2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, Ramiprilum 
A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Angiotensin receptor blockers (ARB) and angiotensin converting enzyme (ACE) inhibitors are known to reduce proteinuria… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE To determine the effect of the angiotensin converting enzyme inhibitor ramipril on the secondary prevention of stroke… (More)
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Highly Cited
2001
Highly Cited
2001
The future rate of cardiovascular events can be predicted by several well-established risk factors. Even in the absence of… (More)
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Highly Cited
2001
Highly Cited
2001
CONTEXT Incidence of end-stage renal disease due to hypertension has increased in recent decades, but the optimal strategy for… (More)
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Highly Cited
2001
Highly Cited
2001
CONTEXT Type 2 diabetes is a growing clinical and public health problem. Preventive efforts related to lifestyle modification are… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Activation of the renin-angiotensin-aldosterone system and oxidative modification of LDL cholesterol play important… (More)
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Highly Cited
2001
Highly Cited
2001
In the HOPE-trial, the ACE inhibitor ramipril significantly reduced cardiovascular morbidity and mortality in patients at high… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Angiotensin-converting-enzyme inhibitors improve the outcome among patients with left ventricular dysfunction, whether… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Diabetes mellitus is a strong risk factor for cardiovascular and renal disease. We investigated whether the… (More)
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