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HLTF gene

Known as: RNF80, HELICASE-LIKE TRANSCRIPTION FACTOR, SUCROSE NONFERMENTING, YEAST, HOMOLOG-LIKE 3 
This gene is involved in chromatin remodeling and regulation of transcription.
National Institutes of Health

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HLTF wt Allele
SMARCA3 protein, humanTranscriptional Regulationchromatin remodelingdna binding

Papers overview

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2019
2019
A germline HLTF mutation in familial MDS induces DNA damage accumulation through impaired PCNA polyubiquitination
Although several causal genes of familial myelodysplastic syndromes (MDS) have been identified, the genetic landscape and the… 
2015
2015
Crystallographic study of a novel DNA-binding domain of human HLTF involved in the template-switching pathway to avoid the replication arrest caused by DNA damage.
HLTF is a pivotal protein in the template-switching pathway that allows DNA synthesis to continue even in the presence of DNA… 
2011
2011
Expression of the helicase‐like transcription factor and its variants during carcinogenesis of the uterine cervix: implications for tumour progression
tumorigenesis in vivo by stimulating expression of vascular endothelial growth factor (VEGF), as well as directly angiogenic… 
2011
2011
Clearance of roadblocks in replication fork restart
To uphold genome stability, cells are armed with sophisticated mechanisms to promote timely and accurate duplication of the… 
2010
2010
CHFR functions as a ubiquitin ligase for HLTF to regulate its stability and functions.
2010
2010
[Hypermethylation of the CDH1, SEPT9, HLTF and ALX4 genes and their diagnostic significance in colorectal cancer].
Sequential treatment of bisulfate-converted DNA was used to study methylation of promoter areas of SEPT9, HLTF, ALX4 and CDH1… 
2010
2010
[Hypermethylation of the CDH1, SEPT9, HLTF and ALX4 genes and their diagnostic significance in colorectal cancer].
Abstract Sequential treatment of bisulfate-converted DNA was used to study methylation of promoter areas of SEPT9, HLTF, ALX4 and… 
2008
2008
Helicase-like transcription factor exhibits increased expression and altered intracellular distribution during tumor progression in hypopharyngeal and laryngeal squamous cell carcinomas
The helicase-like transcription factor (HLTF) belongs to the SWI/SNF family of proteins that use the energy from adenosine… 
2006
2006
Aberrant methylation is frequently observed in advanced esophageal squamous cell carcinoma.
The combined methylation status of the p16, helicase-like transcription factor (HLTF) and T-cadherin, H-cadherin (CDH13) genes in… 
Highly Cited
1997
Highly Cited
1997
Nonisotopic quantitative analysis of protein-DNA interactions at equilibrium.
Two versions of an enzyme-linked immunosorbent assay-type method to quantify protein-DNA interactions at equilibrium were… 
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