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HL60

Known as: HL-60 
HL-60 is a promyelocytic cell line derived by S.J. Collins, et al. Peripheral blood leukocytes were obtained by leukopheresis from a 36-year-old… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and…
Interactions between histone deacetylase inhibitors (HDACIs) and the alkyl-lysophospholipid perifosine were examined in human… 
Highly Cited
1997
Highly Cited
1997
Simultaneous quantitative determination method for sphingolipid metabolites by liquid chromatography/ionspray ionization tandem mass spectrometry.
Sphingolipid metabolites ceramide, sphingomyelin, sphingosine, psycosine, sphingosylphosphorylcholine, and dimethylsphingosine… 
Highly Cited
1992
Highly Cited
1992
Endonuclease activation during apoptosis: the role of cytosolic Ca2+ and pH.
Highly Cited
1992
Highly Cited
1992
Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans.
Highly Cited
1991
Highly Cited
1991
The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells
Granule membrane protein-140 (GMP-140) is an inducible receptor for myeloid leukocytes on activated platelets and endothelium… 
Highly Cited
1988
Highly Cited
1988
Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C.
Highly Cited
1987
Highly Cited
1987
Transcriptional control of the endogenous MYC protooncogene by antisense RNA.
A plasmid carrying antisense human MYC DNA and the gene encoding Escherichia coli xanthine/guanine phosphoribosyltransferase… 
Highly Cited
1986
Highly Cited
1986
Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.
Tumor necrosis factor type alpha (TNF-alpha) is produced by monocytes and has been purified, sequenced, and cloned from the HL-60… 
Highly Cited
1986
Highly Cited
1986
Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60…
Highly Cited
1985
Highly Cited
1985
Role of intracellular calcium mobilization in the regulation of protein kinase C-mediated membrane processes
Phorbol esters are potent tumour-promoting agents that exert pleiotropic effects on cells1–3. Among these are the control of… 
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