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HIV Protease Inhibitors [MoA]

Known as: HIV Protease Inhibitors, Human Immunodeficiency Virus Protease Inhibitors 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A major concern regarding the chronic administration of antiretroviral drugs is the potential for induction of drug efflux… Expand
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Highly Cited
2008
Highly Cited
2008
The plasma concentrations of orally administered anti-human immunodeficiency virus protease inhibitors are significantly reduced… Expand
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Highly Cited
2007
Highly Cited
2007
Human immunodeficiency virus protease inhibitors (PIs) modestly affect the plasma pharmacokinetics of tenofovir (TFV; -15% to +37… Expand
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Highly Cited
2007
Highly Cited
2007
Although many of the clinically significant drug interactions of the anti-human immunodeficiency virus (HIV) protease inhibitors… Expand
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Highly Cited
2006
Highly Cited
2006
Parasite resistance to antimalarial drugs is a serious threat to human health, and novel agents that act on enzymes essential for… Expand
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Highly Cited
2004
Highly Cited
2004
Breast cancer resistance protein (BCRP) is a recently discovered ATP-binding cassette drug transporter. Hence, the full spectrum… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Although recommended as initial therapy for patients with dyslipidemia who are taking human immunodeficiency virus… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Human immunodeficiency virus protease inhibitors (HIV PIs) are associated with hyperlipidemia, hyperglycemia, and… Expand
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Highly Cited
1999
Highly Cited
1999
Highly active antiretroviral therapy that includes human immunodeficiency virus (HIV) aspartyl protease inhibitors (PIs) causes a… Expand
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To assess the pharmacokinetic interaction between ritonavir and saquinavir. METHODS Ritonavir and saquinavir were… Expand
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