• Publications
  • Influence
Vitamin D deficiency.
  • M. Holick
  • Medicine
  • The New England journal of medicine
  • 19 July 2007
TLDR
The role of vitamin D in skeletal and nonskeletal health is considered and strategies for the prevention and treatment ofitamin D deficiency are suggested. Expand
Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.
TLDR
Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances. Expand
Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.
  • M. Holick
  • Medicine
  • The American journal of clinical nutrition
  • 1 December 2004
TLDR
Maintaining blood concentrations of 25-hydroxyvitamin D above 80 nmol/L (approximately 30 ng/mL) not only is important for maximizing intestinal calcium absorption but also may be important for providing the extrarenal 1alpha-hydroxylase that is present in most tissues to produce 1,25-dihydroxyv vitamin D3. Expand
High prevalence of vitamin D inadequacy and implications for health.
  • M. Holick
  • Medicine
  • Mayo Clinic proceedings
  • 1 March 2006
TLDR
The purposes of this article are to examine the prevalence of vitamin D inadequacy and to review the potential implications for skeletal and extraskeletal health. Expand
Decreased bioavailability of vitamin D in obesity.
TLDR
Obese subjects had significantly lower basal 25-hydroxyvitamin D concentrations and higher parathyroid hormone concentrations than did age-matched control subjects and the incremental increase in vitamin D(3) was 57% lower in obese than in nonobese subjects. Expand
Resurrection of vitamin D deficiency and rickets.
  • M. Holick
  • Medicine
  • The Journal of clinical investigation
  • 1 August 2006
TLDR
This review summarizes the role of vitamin D in the prevention of rickets and its importance in the overall health and welfare of infants and children. Expand
Vitamin D deficiency: a worldwide problem with health consequences.
TLDR
Vitamin D deficiency causes rickets in children and will precipitate and exacerbate osteopenia, osteoporosis, and fractures in adults, and foods that are fortified with vitamin D are often inadequate to satisfy either a child's or an adult's vitamin D requirement. Expand
Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis.
  • M. Holick
  • Medicine
  • The American journal of clinical nutrition
  • 1 March 2004
TLDR
Studies in both human and animal models add strength to the hypothesis that the unrecognized epidemic of vitamin D deficiency worldwide is a contributing factor of many chronic debilitating diseases. Expand
Vitamin D status: measurement, interpretation, and clinical application.
  • M. Holick
  • Medicine
  • Annals of epidemiology
  • 1 February 2009
TLDR
The goal should be to maintain both children and adults at a level >30 ng/mL to take full advantage of all the health benefits that vitamin D provides. Expand
Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol.
TLDR
Current recommended vitamin D inputs are inadequate to maintain serum 25-hydroxycholecalciferol concentration in the absence of substantial cutaneous production of vitamin D. Expand
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