Atazanavir

Known as: 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester, Latazanavir, Atazanavirum 
An aza-dipeptide analogue with a bis-aryl substituent on the (hydroxethyl)hydrazine moiety with activity against both wild type and mutant forms of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1958-2017
05010015019582017

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Limited data compare once-daily options for initial therapy for HIV-1. OBJECTIVE To compare time to virologic… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Long-term effects of abacavir (ABC)-lamivudine (3TC), compared with tenofovir (TDF)-emtricitabine (FTC) with efavirenz… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Once-daily atazanavir/ritonavir demonstrated similar antiviral efficacy to twice-daily lopinavir/ritonavir over 48… (More)
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Highly Cited
2010
Highly Cited
2010
In the classical form of alpha1-antitrypsin (AT) deficiency, a point mutation in AT alters the folding of a liver-derived… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Atazanavir/ritonavir is as effective as lopinavir/ritonavir, with a more favourable lipid profile and less… (More)
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Highly Cited
2007
Highly Cited
2007
Diabetes-induced oxidative stress can lead to protein misfolding and degradation by the ubiquitin-proteasome system. This study… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND In BMS Study 045, once-daily (QD) atazanavir/ritonavir (ATV/RTV) demonstrated comparable efficacy and safety to twice… (More)
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Highly Cited
2005
Highly Cited
2005
Several human immunodeficiency virus (HIV) protease inhibitors, including atazanavir, indinavir, lopinavir, nelfinavir, ritonavir… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Atazanavir, an azapeptide protease inhibitor (PI), has pharmacokinetics that allow once-daily dosing, and it is not… (More)
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