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HGG 12

Known as: HGG-12, Pyridinium, 1-(((3-benzoylpyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)-, dichloride 
 
National Institutes of Health

Papers overview

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2007
2007
The oximes HI-6, HLö-7, HGG-12, HGG-42 and obidoxime were used in a previously developed rat model to evaluate the therapeutic… Expand
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1986
1986
Abstract: A study of the effects of bisquaternary pyridinium oximes on calcium‐dependent potassium‐evoked [3H]acetylcholine… Expand
1985
1985
The mode of interaction of bisquaternary pyridinium oximes with rat brain muscarinic receptors in cerebral cortex and brain stem… Expand
Highly Cited
1984
Highly Cited
1984
Acute sc toxicity of soman increased in the order, mice----rats----guinea pigs----dogs, being 12.6 times more toxic to dogs (LD50… Expand
1984
1984
It has been shown that HI-6 was the most potent oxime so far known in poisoning by sarin, VX , and soman, but its protective… Expand
1983
1983
The transient presence of suppressor T cell (Ts) activity in high-dose tolerance to human gamma globulin (HGG), and its (apparent… Expand
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1983
1983
  • J. G. Clement
  • Fundamental and applied toxicology : official…
  • 1983
  • Corpus ID: 45057918
Various oximes (PAM, toxogonin, TMB-4, HS-6, HI-6, HGG-12, HGG-42) combined with atropine were compared as antidotes of soman… Expand
1983
1983
1 The ability of various bis‐pyridinium oximes to restore organophosphate‐inhibited neuromuscular transmission in vitro was… Expand
1979
1979
  • W. Hauser, N. Weger
  • Archives of toxicology. Supplement. = Archiv fur…
  • 1979
  • Corpus ID: 22174919
Therapeutic properties of various combinations of the bispyridinium salts HGG-12 and HGG-42 against soman and sarin poisoning… Expand
Highly Cited
1973
Highly Cited
1973
Studies were performed to define the cellular parameters involved in the interference with the induction of immunologic… Expand
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