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HGG 12

Known as: HGG-12, Pyridinium, 1-(((3-benzoylpyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)-, dichloride 
 
National Institutes of Health

Papers overview

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2007
2007
The oximes HI-6, HLö-7, HGG-12, HGG-42 and obidoxime were used in a previously developed rat model to evaluate the therapeutic… Expand
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1986
1986
A study of the effects of bisquaternary pyridinium oximes on calcium-dependent potassium-evoked [3H]acetylcholine release from… Expand
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1985
1985
The role of the functional substituents on the pyridinium ring of bisquaternary pyridinium compounds, mostly oximes, in exerting… Expand
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1985
1985
The mode of interaction of bisquaternary pyridinium oximes with rat brain muscarinic receptors in cerebral cortex and brain stem… Expand
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1984
1984
Acute sc toxicity of soman increased in the order, mice----rats----guinea pigs----dogs, being 12.6 times more toxic to dogs (LD50… Expand
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1984
1984
It has been shown that HI-6 was the most potent oxime so far known in poisoning by sarin, VX , and soman, but its protective… Expand
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1983
1983
  • John G. Clement
  • Fundamental and applied toxicology : official…
  • 1983
  • Corpus ID: 45057918
Various oximes (PAM, toxogonin, TMB-4, HS-6, HI-6, HGG-12, HGG-42) combined with atropine were compared as antidotes of soman… Expand
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1979
1979
Therapeutic properties of various combinations of the bispyridinium salts HGG-12 and HGG-42 against soman and sarin poisoning… Expand
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1975
1975
Abstract HGG unresponsiveness can be induced in primed A/J mice; however, such induction is difficult and requires multiple… Expand
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1973
1973
Studies were performed to define the cellular parameters involved in the interference with the induction of immunologic… Expand
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