HEXOKINASE

Known as: hexokinase IV, Hexokinase D, Hexokinase [Chemical/Ingredient] 
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Proliferating embryonic and cancer cells preferentially use aerobic glycolysis to support growth, a metabolic alteration commonly… (More)
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Highly Cited
2008
Highly Cited
2008
Cellular bio-energetic metabolism and mitochondria are recognized as potential targets for anticancer agents, due to the numerous… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxia is a pervasive microenvironmental factor that affects normal development as well as tumor progression. In most normal… (More)
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Highly Cited
2004
Highly Cited
2004
The serine/threonine kinase Akt inhibits mitochondrial cytochrome c release and apoptosis induced by a variety of proapoptotic… (More)
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Highly Cited
2004
Highly Cited
2004
In tumour cells, elevated levels of mitochondria-bound isoforms of hexokinase (HK-I and HK-II) result in the evasion of apoptosis… (More)
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Highly Cited
2001
Highly Cited
2001
The rabbit VX2 tumor when implanted in the liver has proven convenient as a model for studying hepatocellular carcinomas. However… (More)
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Highly Cited
2001
Highly Cited
2001
One of the most common signatures of highly malignant tumors is their capacity to metabolize more glucose to lactic acid than… (More)
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Highly Cited
1999
Highly Cited
1999
Sugars are key regulatory molecules that affect diverse processes in higher plants. Hexokinase is the first enzyme in hexose… (More)
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Highly Cited
1997
Highly Cited
1997
The mechanisms by which higher plants recognize and respond to sugars are largely unknown. Here, we present evidence that the… (More)
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Highly Cited
1993
Highly Cited
1993
Kinases that catalyze phosphorylation of sugars, called here sugar kinases, can be divided into at least three distinct… (More)
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