Skip to search formSkip to main contentSkip to account menu

Hexokinase 2

Known as: Hexokinase-2, Muscle, Muscle Form Hexokinase, Hexokinase II 
Hexokinase-2 (917 aa, ~102 kDa) is encoded by the human HK2 gene. This protein plays a role in carbohydrate phosphorylation.
National Institutes of Health

Related topics

Related topics

15 relations
Adipose tissueEnzyme GeneGalactose Metabolism PathwayGlycolysis

Broader (1)

HEXOKINASE

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice
Exercise is a potent physiological stimulus to clear blood glucose from the circulation into skeletal muscle. The mammalian… 
2016
2016
The Roles of Unfolded Protein Response Pathways in Chlamydia Pathogenesis
Chlamydia is an obligate intracellular bacterium that relies on host cells for essential nutrients and adenosine triphosphate… 
2011
2011
Combined RNA Interference of Hexokinase II and 131I-Sodium Iodide Symporter Gene Therapy for Anaplastic Thyroid Carcinoma
The purpose of this study was to investigate the enhanced therapeutic effect of the combined use of shRNA (small hairpin RNA… 
Highly Cited
2001
Highly Cited
2001
Hexokinase isozyme distribution in human skeletal muscle.
Two isoforms of hexokinase (type I and type II) are expressed in skeletal muscle; however, the intracellular distribution of… 
2000
2000
Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern
Abstract. In mammalian tissues, the phosphorylation of intracellular glucose to glucose-6-phosphate (Glu-6-P) is facilitated by… 
Highly Cited
1996
Highly Cited
1996
Identification and Characterization of Basal and Cyclic AMP Response Elements in the Promoter of the Rat Hexokinase II Gene*
Hexokinases catalyze the phosphorylation of glucose and initiate cellular glucose metabolism. Hexokinase II (HKII) is the… 
Highly Cited
1996
Highly Cited
1996
Overexpression of Hexokinase II in Transgenic Mice
Hexokinase II (HKII) is the predominant isozyme expressed in peripheral insulin-responsive tissues. To explore the role of HKII… 
Highly Cited
1994
Highly Cited
1994
Low-frequency stimulation of rat fast-twitch muscle enhances the expression of hexokinase II and both the translocation and expression of glucose transporter 4 (GLUT-4).
This study followed changes in the capacities of uptake and phosphorylation of glucose in response to contractile activity in low… 
Highly Cited
1993
Highly Cited
1993
Regulation of glucose transporter and hexokinase II expression in tissues of diabetic rats.
Glucose transport and phosphorylation are decreased in muscle and adipose tissue in diabetes mellitus. The glucose transporter… 
1979
1979
Distribution of hexokinase isoenzymes depending on a carbon source in Saccharomyces cerevisiae.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)