Hexokinase 2

Known as: Hexokinase-2, Muscle, Muscle Form Hexokinase, Hexokinase II 
Hexokinase-2 (917 aa, ~102 kDa) is encoded by the human HK2 gene. This protein plays a role in carbohydrate phosphorylation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Accelerated glucose metabolism is a common feature of cancer cells. Hexokinases catalyze the first committed step of glucose… (More)
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2013
2013
BACKGROUND While aerobic glycolysis is linked to unconstrained proliferation in cancer, less is known about its physiological… (More)
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Highly Cited
2009
Highly Cited
2009
It has long been observed that cancer cells rely more on glycolysis to generate ATP and actively use certain glycolytic metabolic… (More)
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Highly Cited
2007
Highly Cited
2007
We investigated the role of AMPKalpha2in basal, exercise training-, and AICAR-induced protein expression of GLUT4, hexokinase II… (More)
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Highly Cited
2005
Highly Cited
2005
Transformed cells are highly glycolytic and overexpress hexokinase II (HXK II). HXK II is capable of binding to the mitochondria… (More)
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2005
2005
AIM Myostatin has been characterized as a negative regulator of skeletal muscle growth. To examine a probable function of… (More)
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Highly Cited
2003
Highly Cited
2003
Endurance exercise training induces mitochondrial biogenesis in skeletal muscle. The peroxisome proliferator activated receptor… (More)
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2001
2001
Two isoforms of hexokinase (type I and type II) are expressed in skeletal muscle; however, the intracellular distribution of… (More)
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Highly Cited
1999
Highly Cited
1999
The hypothesis of this investigation was that glucose uptake would be increased in skeletal muscle of transgenic mice (TG… (More)
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Highly Cited
1993
Highly Cited
1993
A DNA segment that is highly conserved in glucokinase (hexokinase IV) and hexokinase I cDNA was used to identify specific cDNAs… (More)
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