Glucokinase

Known as: ATP:D-glucose 6-phosphotransferase, Glucokinase [Chemical/Ingredient] 
A group of enzymes that catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate. They are found in invertebrates and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2018
010203019592018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mammalian target of rapamycin complex 2 (mTORC2) phosphorylates and activates AGC kinase family members, including Akt, SGK1, and… (More)
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Highly Cited
2006
Highly Cited
2006
AMP-activated protein kinase (AMPK) controls glucose uptake and glycolysis in muscle. Little is known about its role in liver… (More)
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Highly Cited
2004
Highly Cited
2004
Glucokinase is a monomeric enzyme that displays a low affinity for glucose and a sigmoidal saturation curve for its substrate… (More)
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Highly Cited
2004
Highly Cited
2004
Glucokinase (GK) is a glycolytic key enzyme that functions as a glucose sensor in the pancreatic beta-cell, where it governs… (More)
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Highly Cited
2003
Highly Cited
2003
Glucokinase (GK) plays a key role in whole-body glucose homeostasis by catalyzing the phosphorylation of glucose in cells that… (More)
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Highly Cited
2002
Highly Cited
2002
Specialized neurons utilize glucose as a signaling molecule to alter their firing rate. Glucose-excited (GE) neurons increase and… (More)
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Highly Cited
1996
Highly Cited
1996
All glucokinase gene mutations identified to date have been localized to exons that are common to the pancreatic and hepatic… (More)
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Highly Cited
1995
Highly Cited
1995
The secretion of insulin is controlled by the rate of glucose metabolism in the pancreatic beta cells. As phosphorylation by… (More)
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Highly Cited
1992
Highly Cited
1992
DNA polymorphisms in the glucokinase gene have recently been shown to be tightly linked to early-onset non-insulin-dependent… (More)
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Highly Cited
1975
Highly Cited
1975
Genetic studies show that Escherichia coli has three enzymes capable of phosphorylating glucose: soluble adenosine 5… (More)
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