GCK gene

Known as: HEXOKINASE 4, GLUCOKINASE, HK4 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
05010015019512017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mammalian target of rapamycin complex 2 (mTORC2) phosphorylates and activates AGC kinase family members, including Akt, SGK1, and… (More)
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Highly Cited
2004
Highly Cited
2004
Hepatic glucokinase (GK) catalyzes the phosphorylation of glucose to glucose 6-phosphate (G6P), a step which is essential for… (More)
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Highly Cited
2003
Highly Cited
2003
Glycolysis and apoptosis are considered major but independent pathways that are critical for cell survival. The activity of BAD… (More)
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Highly Cited
2002
Highly Cited
2002
Complete lack of transcription factor PDX-1 leads to pancreatic agenesis, whereas heterozygosity for PDX-1 mutations has been… (More)
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Highly Cited
1999
Highly Cited
1999
Glucokinase (GK) gene mutations cause diabetes mellitus in both humans and mouse models, but the pathophysiological basis is only… (More)
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Highly Cited
1999
Highly Cited
1999
Hepatic glucokinase plays a key role in glucose metabolism as underlined by the anomalies associated with glucokinase mutations… (More)
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Highly Cited
1998
Highly Cited
1998
 
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Highly Cited
1997
Highly Cited
1997
To elucidate cellular mechanisms of insulin resistance induced by excess dietary fat, we studied conscious chronically high-fat… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND AND METHODS Non-insulin-dependent diabetes mellitus (NIDDM) is a genetically heterogeneous disorder. Maturity-onset… (More)
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Highly Cited
1992
Highly Cited
1992
MATURITY-ONSET diabetes of the young (MODY) is a form of non-insulin-dependent (type 2) diabetes mellitus (NIDDM) which is… (More)
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