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GCK gene

Known as: HEXOKINASE 4, GLUCOKINASE, HK4 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Glucokinase is a key regulatory enzyme in the pancreatic beta‐cell. It plays a crucial role in the regulation of insulin… Expand
Highly Cited
2003
Highly Cited
2003
Glycolysis and apoptosis are considered major but independent pathways that are critical for cell survival. The activity of BAD… Expand
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Review
2001
Review
2001
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of disorders characterized by nonketotic diabetes… Expand
Highly Cited
1999
Highly Cited
1999
Glucokinase (GK) gene mutations cause diabetes mellitus in both humans and mouse models, but the pathophysiological basis is only… Expand
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Review
1999
Review
1999
SUMMARY Glucose, the most abundant monosaccharide in nature, is the principal carbon and energy source for nearly all cells. The… Expand
Highly Cited
1999
Highly Cited
1999
Hepatic glucokinase plays a key role in glucose metabolism as underlined by the anomalies associated with glucokinase mutations… Expand
Highly Cited
1998
Highly Cited
1998
Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin… Expand
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Review
1996
Review
1996
Special features of glucose metabolism in pancreatic β-cells are central to an understanding of the physiological role of these… Expand
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Highly Cited
1993
Highly Cited
1993
BACKGROUND AND METHODS Non-insulin-dependent diabetes mellitus (NIDDM) is a genetically heterogeneous disorder. Maturity-onset… Expand
Highly Cited
1992
Highly Cited
1992
MATURITY-ONSET diabetes of the young (MODY) is a form of non-insulin-dependent (type 2) diabetes mellitus (NIDDM) which is… Expand