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Glucokinase is a key regulatory enzyme in the pancreatic beta‐cell. It plays a crucial role in the regulation of insulin… Expand Glycolysis and apoptosis are considered major but independent pathways that are critical for cell survival. The activity of BAD… Expand Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of disorders characterized by nonketotic diabetes… Expand Glucokinase (GK) gene mutations cause diabetes mellitus in both humans and mouse models, but the pathophysiological basis is only… Expand SUMMARY Glucose, the most abundant monosaccharide in nature, is the principal carbon and energy source for nearly all cells. The… Expand Hepatic glucokinase plays a key role in glucose metabolism as underlined by the anomalies associated with glucokinase mutations… Expand Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin… Expand Special features of glucose metabolism in pancreatic β-cells are central to an understanding of the physiological role of these… Expand BACKGROUND AND METHODS
Non-insulin-dependent diabetes mellitus (NIDDM) is a genetically heterogeneous disorder. Maturity-onset… Expand MATURITY-ONSET diabetes of the young (MODY) is a form of non-insulin-dependent (type 2) diabetes mellitus (NIDDM) which is… Expand