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MAP4K1 gene

Known as: HEMATOPOIETIC PROGENITOR KINASE 1, MAP4K1, HPK1 
National Institutes of Health

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Related topics

1 relation
GCK gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Identifying hub genes of clear cell renal cell carcinoma associated with the proportion of regulatory T cells by weighted gene co-expression network analysis
Background: Numerous patients with clear cell renal cell carcinoma (ccRCC) experience drug resistance after immunotherapy… 
2019
2019
Abstract 2693: Targeting the Hippo-YAP pathway with novel small-molecule inhibitors of the YAP-TEAD transcription activity
We have discovered and are developing multiple novel small molecule medicines targeting the Hippo-YAP pathway. Consisting of… 
2015
2015
[Interactions between MAP4K1 and adaptor proteins].
Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1, also called hematopoietic progenitor kinase 1, HPK1) is a serine… 
2012
2012
The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells.
2012
2012
The impact of either 4-R-hydroxyproline or 4-R-fluoroproline on the conformation and SH3m-cort binding of HPK1 proline-rich peptide
SH3 domains are probably the most abundant molecular-recognition modules of the proteome. A common feature of these domains is… 
2011
2011
The SLP-76 Src Homology 2 Domain Is Required for T Cell Development and Activation
The adapter protein Src homology 2 (SH2) domain-containing leukocyte protein of 76 kDa (SLP-76) is critical for multiple aspects… 
2009
2009
Recognition of lysine‐rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies
Cortactin is a ubiquitous actin‐binding protein that regulates various aspects of cell dynamics and is implicated in the… 
2006
2006
Choroidal neovascularization in transgenic mice expressing prokineticin 1: an animal model for age-related macular degeneration.
2002
2002
Phage Display Based Cloning of Proteins Interacting with the Cytoplasmic Tail of Membrane Immunoglobulins
The reduced quantity and quality of serum immunoglobulins (sIgs) in mutant mice expressing truncated cytoplasmic tails of IgE and… 
1972
1972
An analysis of chromosomal sensitivity of HPK1 cells from the marsupial Potorous tridactylus to x-rays and to heliotrine.
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