J. Ashmore

Publications122
h-index32
Citations3,799
Highly Influential Citations15
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Regulation of insulin secretion.
  • 130
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Hexokinase, glucose-6-phosphatase and phosphorylase levels in hereditarily obese-hyperglycemic mice.
Abstract The skeletal muscle and kidney hexokinase activities of the obesehyperglycemic mice and their nonobese controls were of the same magnitude. The liver glucose-6-phosphatase activities per… Expand
  • 126
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Isotope studies on the pathways of glucose-6-phosphate metabolism in the Novikoff hepatoma.
The metabolism of glucose-6-phosphate in normal rat liver and Novikoff hepatoma slices was studied by utilization of glucose-1-C14 and glucose-6-C14. The tissue slices were incubated in two different… Expand
  • 42
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Effects of adrenergic and cholinergic agents upon insulin secretion in vitro.
Adrenergic drugs (epinephrine, norepinephrine and isoproterenol) inhibit insulin secretion from pieces of rat pancreas incubated with glucose (150 mg/100 ml). This inhibitory effect appears to be… Expand
  • 255
  • 1
Glucose penetration into liver.
To further define the action of insulin on liver metabolism, studies were undertaken to determine whether the cell wall could be the site of action as has been proposed for muscle. Control rats and...
  • 247
  • 1
Studies on carbohydrate metabolism in rat liver slices. IX. Ionic and hormonal effects on phosphorylase and glycogen.
  • 46
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Blood glucose and the liver.
Abstract A graphical summary of those aspects of carbohydrate metabolism herein discussed, which contribute to the regulation of blood glucose under normal and pathological conditions, is presented… Expand
  • 218
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The effect of insulin on hepatic glucose metabolism in the unanesthetized dog.
  • 47
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Ketogenic and lipolytic effects of glucagon on liver.
Abstract The glycogenolytic effect of glucagon on liver has been extensively investigated. Increased glycogen breakdown and glucose production are apparent after both in vivo and in vitro… Expand
  • 96
  • 1
The metabolism of drugs in isolated rat hepatocytes. A comparison with in vivo drug metabolism and drug metabolism in subcellular liver fractions.
The metabolism of drugs in isolated rat hepatocytes has been investigated. Drugs which are metabolized by aromatic hydrolation, aliphatic hydroylation, N-demethylation, or glucuronidation have been… Expand
  • 106
  • 1