HAMP gene

Known as: Hepcidin Antimicrobial Peptide Gene, LEAP1, LEAP-1 
This gene is involved in both iron metabolism and antimicrobial activity.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND OBJECTIVES Hepcidin is a key regulator of iron homeostasis, but its study in the setting of chronic kidney disease… (More)
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Highly Cited
2009
Highly Cited
2009
Hepcidin is a critical inhibitor of iron export from macrophages, enterocytes, and hepatocytes. Given that it is filtered and… (More)
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Review
2009
Review
2009
Ovarian carcinomas are a heterogeneous group of neoplasms and are traditionally subclassified based on type and degree of… (More)
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Highly Cited
2005
Highly Cited
2005
Ferroportin (FPN) mediates iron export from cells; FPN mutations are associated with the iron overloading disorder… (More)
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Highly Cited
2004
Highly Cited
2004
Hepcidin is a peptide hormone secreted by the liver in response to iron loading and inflammation. Decreased hepcidin leads to… (More)
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Highly Cited
2004
Highly Cited
2004
Miltefosine (hexadecylphosphocholine [HePC]) has proved to be a potent oral treatment for human visceral leishmaniasis due to… (More)
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Highly Cited
2003
Highly Cited
2003
Haemochromatosis (HH) is a clinically and genetically heterogeneous disease caused by inappropriate iron absorption. Most HH… (More)
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Highly Cited
2003
Highly Cited
2003
Hepcidin is a liver-made peptide proposed to be a central regulator of intestinal iron absorption and iron recycling by… (More)
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Highly Cited
2001
Highly Cited
2001
Considering that the development of hepatic lesions related to iron overload diseases might be a result of abnormally expressed… (More)
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Highly Cited
2001
Highly Cited
2001
Cysteine-rich antimicrobial peptides are abundant in animal and plant tissues involved in host defense. In insects, most are… (More)
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