hepcidin

Known as: Hepcidins, LEAP-1, Liver-Expressed Antimicrobial Peptide 
Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Under evolutionary pressure to counter the toxicity of iron and to maintain adequate iron supply for hemoglobin synthesis and… (More)
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Highly Cited
2008
Highly Cited
2008
We developed and validated the first serum enzyme-linked immunosorbent assay for hepcidin, the principal iron-regulatory hormone… (More)
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Highly Cited
2006
Highly Cited
2006
Hepcidin is a key regulator of systemic iron homeostasis. Hepcidin deficiency induces iron overload, whereas hepcidin excess… (More)
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Highly Cited
2004
Highly Cited
2004
Hepcidin is a peptide hormone secreted by the liver in response to iron loading and inflammation. Decreased hepcidin leads to… (More)
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Highly Cited
2004
Highly Cited
2004
Hypoferremia is a common response to systemic infections or generalized inflammatory disorders. In mouse models, the development… (More)
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Highly Cited
2003
Highly Cited
2003
Hepcidin is a liver-made peptide proposed to be a central regulator of intestinal iron absorption and iron recycling by… (More)
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Review
2003
Review
2003
Human hepcidin, a 25-amino acid peptide made by hepatocytes, may be a new mediator of innate immunity and the long-sought iron… (More)
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Highly Cited
2002
Highly Cited
2002
The present study was aimed at determining whether hepcidin, a recently identified peptide involved in iron metabolism, plays a… (More)
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Highly Cited
2002
Highly Cited
2002
We recently reported the hemochromatosis-like phenotype observed in our Usf2 knockout mice. In these mice, as in murine models of… (More)
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Highly Cited
2001
Highly Cited
2001
Considering that the development of hepatic lesions related to iron overload diseases might be a result of abnormally expressed… (More)
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