Guanylin, human

Known as: Guanylin, Guanylate Cyclase-Activating Protein I, Guanylate Cyclase-Activating Protein 1 
Guanylin (115 aa, ~12 kDa) is encoded by the human GUCA2A gene. This protein plays a role in the activation of intestinal guanylate cyclase.
National Institutes of Health

Papers overview

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2003
2003
As the intestine is an essential organ for fish osmoregulation, the intestinal hormone guanylins may perform major functions… (More)
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Highly Cited
2002
Highly Cited
2002
Heat-stable enterotoxin (STa), elaborated by enterotoxigenic Echerichia coli, is a worldwide cause of secretory diarrhea in… (More)
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Review
2000
Review
2000
The guanylin family of cGMP-regulating peptides has three subclasses of peptides containing either three intramolecular… (More)
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1998
1998
Guanylin is a mammalian peptide ligand that binds to the enterocyte receptor guanylyl cyclase C and mediates Cl- and HCO3- efflux… (More)
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1997
1997
Guanylin and uroguanylin are peptides that stimulate membrane guanylate cyclases (GC) and regulate intestinal and renal function… (More)
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Review
1995
Review
1995
Regulation of intestinal salt and water transport is critical to the maintenance of fluid volume. Control of this life-sustaining… (More)
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1994
1994
Guanylin, a peptide homologue of the bacterial heat-stable enterotoxins (ST), is an endogenous activator of guanylate cyclase C… (More)
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1993
1993
Intestinal salt and fluid secretion is stimulated by Escherichia coli heat-stable enterotoxins (ST) through activation of a… (More)
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Highly Cited
1992
Highly Cited
1992
Intestinal guanylate cyclase mediates the action of the heat-stable enterotoxin to cause a decrease in intestinal fluid… (More)
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1992
1992
Heat-stable enterotoxins (STa) are small, cysteine-rich peptides secreted by Escherichia coli that are able to induce diarrhea… (More)
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