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GUCA2A gene

Known as: GUANYLIN, STARA, prepro-guanylin 
This gene plays a role in the positive regulation of intestinal guanylate cyclase.
National Institutes of Health

Related topics

Related topics

5 relations
Enzyme InductionGUCA1B geneGUCA2A wt AlleleGuanylate Cyclase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
The Proximal Convoluted Tubule is a Target for the Uroguanylin-regulated Natriuretic Response
Objectives and Methods: Guanylin and uroguanylin are peptides synthesized in the intestine and kidney that are postulated to have… 
Highly Cited
2002
Highly Cited
2002
Guanylin, Uroguanylin, and Heat-stable Euterotoxin Activate Guanylate Cyclase C and/or a Pertussis Toxin-sensitive G Protein in Human Proximal Tubule Cells*
Membrane guanylate cyclase C (GC-C) is the receptor for guanylin, uroguanylin, and heat-stable enterotoxin (STa) in the intestine… 
2002
2002
The Electrolyte/Fluid Secretion Stimulatory Peptides Guanylin and Uroguanylin and Their Common Functional Coupling Proteins in the Rat Pancreas: A Correlative Study of Expression and Cell-Specific…
Introduction Guanylin and uroguanylin are intestinal or urine peptides that stimulate epithelial electrolyte/fluid secretion by… 
2001
2001
Activation of Angiotensin II Subtype 2 Receptor Induces Catecholamine Release in an Extracellular Ca2+-Dependent Manner through a Decrease of Cyclic Guanosine 3',5'-Monophosphate Production in…
We have previously demonstrated that CGP 42112 (AT2 agonist: ≧1 nm) markedly reduces catecholamine biosynthesis through AT2… 
1998
1998
Uroguanylin: Gene structure, expression, processing as a peptide hormone, and co-storage with somatostatin in gastrointestinal D-cells
Highly Cited
1995
Highly Cited
1995
Analysis of the human guanylin gene and the processing and cellular localization of the peptide.
The complete cell biological analysis of human guanylin, a recently discovered regulatory peptide, is offered in this… 
1995
1995
Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35.
Highly Cited
1994
Highly Cited
1994
Enterochromaffin cells of the digestive system: cellular source of guanylin, a guanylate cyclase-activating peptide.
Guanylin, a bioactive peptide, has recently been isolated from the intestine; this peptide activates intestinal guanylate cyclase… 
1994
1994
Upregulation of Escherichia coli heat-stable enterotoxin receptor in regenerating rat liver.
Guanylate cyclase C (GC-C) is a transmembrane protein that serves as a receptor for the recently characterized endogenous ligand… 
Highly Cited
1992
Highly Cited
1992
Human guanylin: cDNA isolation, structure, and activity
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