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Guanylate Cyclase
Known as:
EC 4.6.1.2
, Guanylate Cyclase [Chemical/Ingredient]
, Guanyl Cyclase
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Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are…
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National Institutes of Health
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Related topics
Related topics
32 relations
Narrower (11)
CARD11 protein, human
CARD14 protein, human
GC-G protein, mouse
GCY-23 protein, C elegans
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GUCA1A gene
GUCA1B gene
GUCA1C gene
GUCA2A gene
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Broader (1)
Phosphorus-Oxygen Lyases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Proteomic Analysis of S-Nitrosylated Proteins in Mesangial Cells *
T. Kuncewicz
,
E. Sheta
,
I. Goldknopf
,
B. Kone
Molecular & Cellular Proteomics
2003
Corpus ID: 18088999
NO participates in numerous biological events in a variety of cell types including activated glomerular mesangial cells. Many of…
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Highly Cited
1996
Highly Cited
1996
Localization of natriuretic peptide‐activated guanylate cyclase mRNAs in the rat brain
J P Herman
,
C. M. Dolgas
,
D. Rucker
,
M. Langub
The Journal of comparative neurology
1996
Corpus ID: 7645348
Physiological actions of atrial natriuretic peptide (ANP) and C‐type natriuretic peptide (CNP) are elaborated by membrane‐bound…
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Review
1994
Review
1994
The guanylyl cyclase receptors.
Naohisa Tamura
,
D. L. Garbers
Zygote (Cambridge. Print)
1994
Corpus ID: 43011541
Review
1992
Review
1992
Receptor guanylyl cyclases.
S. Wong
,
D. Garbers
Journal of Clinical Investigation
1992
Corpus ID: 20176475
Three different guanylyl cyclase cell receptors are known, but others will likely be discovered within the next few years. The…
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Highly Cited
1988
Highly Cited
1988
Age-related differences in receptors for Escherichia coli heat-stable enterotoxin in the small and large intestine of children.
M. Cohen
,
A. Guarino
,
R. Shukla
,
R. Giannella
Gastroenterology
1988
Corpus ID: 21405382
Highly Cited
1985
Highly Cited
1985
Effects of extracellular egg factors on sperm guanylate cyclase.
G. Ward
,
D. Garbers
,
V. Vacquier
Science
1985
Corpus ID: 42685041
Extracellular factors from the sea urchin egg induce a change in the electrophoretic mobility of an abundant sperm membrane…
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Highly Cited
1978
Highly Cited
1978
Enzymatic regulation of the concentration of cyclic GMP in mouse brain
L. Greenberg
,
E. Troyer
,
J. Ferrendelli
,
B. Weiss
Neuropharmacology
1978
Corpus ID: 36218826
Highly Cited
1975
Highly Cited
1975
Increases in cyclic GMP levels in brain and liver with sodium azide an activator of guanylate cyclase
H. Kimura
,
C. K. Mittal
,
F. Murad
Nature
1975
Corpus ID: 115294
SODIUM azide produces extrapyramidal symptoms with necrosis of the cerebral cortex, cerebellum, and basal ganglia. Toxicity with…
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Highly Cited
1974
Highly Cited
1974
Separation and purification of cyclic nucleotides by alumina column chromatography.
A. A. White
Methods in Enzymology
1974
Corpus ID: 8175032
Highly Cited
1972
Highly Cited
1972
CYTOCHEMICAL LOCALIZATION OF ADENYL CYCLASE ACTIVITY IN RAT ISLETS OF LANGERHANS
S. Howell
,
M. Whitfield
Journal of Histochemistry and Cytochemistry
1972
Corpus ID: 6722165
A cytochemical method has been used to investigate the localization of adenyl cyclase activity in A and B cells of isolated rat…
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