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Guanylate Cyclase

Known as: EC 4.6.1.2, Guanylate Cyclase [Chemical/Ingredient], Guanyl Cyclase 
Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine nitration. Peroxynitrite is the product… Expand
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Review
2018
Review
2018
ABSTRACT Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm Hg or above. This review deals… Expand
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Review
2017
Review
2017
Adenylyl cyclases (ACs) generate the second messenger cAMP from ATP. Mammalian cells express nine transmembrane AC (mAC) isoforms… Expand
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Review
2011
Review
2011
Soluble guanylate cyclase (sGC), a key enzyme of the nitric oxide (NO) signaling pathway, is attracting rapidly growing interest… Expand
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Highly Cited
2004
Highly Cited
2004
Specialized oxygen-sensing cells in the nervous system generate rapid behavioural responses to oxygen. We show here that the… Expand
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Highly Cited
2004
Highly Cited
2004
Pole development is coordinated with the Caulobacter crescentus cell cycle by two-component signaling proteins. We show that an… Expand
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Highly Cited
2001
Highly Cited
2001
Nitric oxide (NO) is a widespread, potent, biological mediator that has many physiological and pathophysiological roles. Research… Expand
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Highly Cited
1991
Highly Cited
1991
NADPH diaphorase histochemistry selectively labels a number of discrete populations of neurons throughout the nervous system… Expand
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Review
1991
Review
1991
Nitric oxide (NO) is a recently discovered and highly unorthodox messenger molecule. Current evidence indicates that, in the CNS… Expand
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Highly Cited
1989
Highly Cited
1989
A soluble enzyme obtained from rat forebrain catalyzes the NADPH-dependent formation of nitric oxide (NO) and citrulline from L… Expand
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