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Guanylate Cyclase

Known as: EC 4.6.1.2, Guanylate Cyclase [Chemical/Ingredient], Guanyl Cyclase 
Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). Impaired bioavailability and… Expand
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Highly Cited
2004
Highly Cited
2004
Pole development is coordinated with the Caulobacter crescentus cell cycle by two-component signaling proteins. We show that an… Expand
Highly Cited
2004
Highly Cited
2004
Specialized oxygen-sensing cells in the nervous system generate rapid behavioural responses to oxygen. We show here that the… Expand
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Highly Cited
2000
Highly Cited
2000
The stress-inducible protein heme oxygenase-1 provides protection against oxidative stress. The anti-inflammatory properties of… Expand
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Review
1999
Review
1999
Signal transduction with the diatomic radical nitric oxide (NO) is involved in a number of important physiological processes… Expand
Highly Cited
1994
Highly Cited
1994
Nitric oxide (.NO) is a recently discovered signaling agent which plays a role in many biological processes such as vasodilation… Expand
Highly Cited
1992
Highly Cited
1992
The NADPH-diaphorase histochemical technique provides a simple and robust method to stain select populations of neurons… Expand
Highly Cited
1991
Highly Cited
1991
NADPH diaphorase histochemistry selectively labels a number of discrete populations of neurons throughout the nervous system… Expand
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Highly Cited
1989
Highly Cited
1989
A soluble enzyme obtained from rat forebrain catalyzes the NADPH-dependent formation of nitric oxide (NO) and citrulline from L… Expand
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Highly Cited
1987
Highly Cited
1987
Organic nitrates develop their vasodilating potency by stimulating the enzyme guanylate cyclase. There are still several theories… Expand