Guanylate Cyclase

Known as: EC 4.6.1.2, Guanylate Cyclase [Chemical/Ingredient], Guanyl Cyclase 
Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are… (More)

Topic mentions per year

Topic mentions per year

1969-2017
020040019692017

Papers overview

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Review
2016
Review
2016
The most common forms of pulmonary hypertension are pulmonary arterial hypertension, chronic thromboembolic pulmonary… (More)
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Highly Cited
2004
Highly Cited
2004
Specialized oxygen-sensing cells in the nervous system generate rapid behavioural responses to oxygen. We show here that the… (More)
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Highly Cited
2004
Highly Cited
2004
Pole development is coordinated with the Caulobacter crescentus cell cycle by two-component signaling proteins. We show that an… (More)
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Highly Cited
2001
Highly Cited
2001
Nitric oxide (NO) is a widespread, potent, biological mediator that has many physiological and pathophysiological roles. Research… (More)
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Highly Cited
1996
Highly Cited
1996
Leber's congenital amaurosis (LCA, MIM 2040001), the earliest and most severe form of inherited retinopathy, accounts for at… (More)
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Highly Cited
1994
Highly Cited
1994
YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] inhibited the aggregation of and ATP release from washed rabbit platelets… (More)
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Highly Cited
1992
Highly Cited
1992
Intestinal guanylate cyclase mediates the action of the heat-stable enterotoxin to cause a decrease in intestinal fluid… (More)
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Highly Cited
1989
Highly Cited
1989
Atrial natriuretic peptide (ANP) is a polypeptide hormone whose effects include the induction of diuresis, natriuresis and… (More)
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Highly Cited
1989
Highly Cited
1989
A soluble enzyme obtained from rat forebrain catalyzes the NADPH-dependent formation of nitric oxide (NO) and citrulline from L… (More)
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Highly Cited
1977
Highly Cited
1977
Nitric oxide gas (NO) increased guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] activity in soluble and… (More)
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