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Golgi-Associated PDZ and Coiled-Coil Motif-Containing Protein

Known as: PDZ Protein Interacting Specifically with TC10, Fused in Glioblastoma, PIST 
Golgi-associated PDZ and coiled-coil motif-containing protein (462 aa, ~51 kDa) is encoded by the human GOPC gene. This protein plays a role in… 
National Institutes of Health

Related topics

Related topics

10 relations
Cellular MembraneCoiled-Coil DomainGOPC geneGOPC wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Sustained Autophagy Contributes to Measles Virus Infectivity
The interplay between autophagy and intracellular pathogens is intricate as autophagy is an essential cellular response to fight… 
Review
2013
Review
2013
The role of ion channels and transporters in cell proliferation and cancer
After the early wavering steps tracing back to at least the 1960's (Cone, 1974; Binggeli and Cameron, 1980), the study of ion… 
Highly Cited
2012
Highly Cited
2012
Identification of KIF5B-RET and GOPC-ROS1 Fusions in Lung Adenocarcinomas through a Comprehensive mRNA-Based Screen for Tyrosine Kinase Fusions
Background: The mutually exclusive pattern of the major driver oncogenes in lung cancer suggests that other mutually exclusive… 
Highly Cited
2012
Highly Cited
2012
Endoproteolytic Cleavage of TUG Protein Regulates GLUT4 Glucose Transporter Translocation*
Background: GLUT4 glucose transporters are trapped and sequestered intracellularly in adipocytes by TUG. Results: Insulin… 
Highly Cited
2005
Highly Cited
2005
Interactions with PDZ Domain Proteins PIST/GOPC and PDZK1 Regulate Intracellular Sorting of the Somatostatin Receptor Subtype 5*
By yeast two-hybrid screening we have identified interaction partners for the intracellular C-terminal tail of the human and… 
Highly Cited
2004
Highly Cited
2004
PSD-95 and Lin-7b Interact with Acid-sensing Ion Channel-3 and Have Opposite Effects on H+-gated Current*
The acid-sensing ion channel-3 (ASIC3) is a degenerin/epithelial sodium channel expressed in the peripheral nervous system… 
Highly Cited
2004
Highly Cited
2004
Interaction with Cystic Fibrosis Transmembrane Conductance Regulator-associated Ligand (CAL) Inhibits β1-Adrenergic Receptor Surface Expression*
G protein-coupled receptors such as the β1-adrenergic receptor (β1AR) must be trafficked to the plasma membrane in order to bind… 
Highly Cited
2002
Highly Cited
2002
Lack of acrosome formation in mice lacking a Golgi protein, GOPC
The acrosome is a unique organelle that plays an important role at the site of sperm–zona pellucida binding during the… 
Highly Cited
2001
Highly Cited
2001
PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10.
TC10 is a member of the Rho family of GTPases, most closely related to Cdc42. This family of proteins mediates cytoskeletal… 
Highly Cited
2001
Highly Cited
2001
Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled.
The frizzled gene is evolutionally conserved in a wide variety of organisms including mammals, and in Drosophila, frizzled is… 
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