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Glycocholic Acid

Known as: Cholylglycine, Glycine, N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)-, Glycocholic Acid [Chemical/Ingredient] 
The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

Cholagogues and CholereticsDetergentscholate
Cholylglycine.conjugated:MCnc:Pt:Ser:QnCholylglycine:MCnc:Pt:Ser:QnIn BloodProcess of secretion

Narrower (5)

Glycine CholateGlycocholate Sodiumcholylglycylhistaminecholylglycyltyrosine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il 10 2 / 2 mice
The composite human microbiome of Western populations has probably changed over the past century, brought on by new environmental… 
Highly Cited
1997
Highly Cited
1997
Composition and concentration of bile acid reflux into the esophagus of patients with gastroesophageal reflux disease.
Highly Cited
1991
Highly Cited
1991
Effect of dietary lipid and vitamin E on mitochondrial lipid peroxidation and hepatic injury in the bile duct-ligated rat.
To assess whether lipid peroxidation of hepatic mitochondria is associated with cholestatic hepatic injury we examined the effect… 
Highly Cited
1983
Highly Cited
1983
Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man.
A multicompartmental pharmacokinetic model based on physiological principles, experimental data, and the standard mathematical… 
Highly Cited
1981
Highly Cited
1981
Physiologic cholestasis: Elevation of the primary serum bile acid concentrations in normal infants
Highly Cited
1981
Highly Cited
1981
Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants.
Immaturity of hepatic excretory function resulting in a period of "physiologic cholestasis" may occur during early life. Serum… 
Highly Cited
1976
Highly Cited
1976
Purification and characterization of bile salt hydrolase from Bacteroides fragilis subsp. fragilis.
Highly Cited
1976
Highly Cited
1976
Comparison of the binding of various bile acids and bile salts in vitro by several types of fiber.
The binding in vitro of the sodium salts of cholic acid, chenodeoxycholic acid, deoxycholic acid, taurocholic acid… 
Highly Cited
1973
Highly Cited
1973
Effect of glycine-conjugated bile acids with and without lecithin on water and glucose absorption in perfused human jejunum.
Perfusion studies were performed in healthy volunteers to test whether the secretory effect of conjugated bile acids, previously… 
Highly Cited
1972
Highly Cited
1972
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. I. Cholylglycine.
Cholyl-2,4-(3)H-glycine-1-(14)C was administered orally to eight healthy subjects with indwelling nasoduodenal tubes. The… 
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