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Glycocholic Acid

Known as: Cholylglycine, Glycine, N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)-, Glycocholic Acid [Chemical/Ingredient] 
The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

Cholagogues and CholereticsDetergentscholate
Cholylglycine.conjugated:MCnc:Pt:Ser:QnCholylglycine:MCnc:Pt:Ser:QnIn BloodProcess of secretion

Narrower (5)

Glycine CholateGlycocholate Sodiumcholylglycylhistaminecholylglycyltyrosine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
A Clinical Single-Pass Perfusion Investigation of the Dynamic in Vivo Secretory Response to a Dietary Meal in Human Proximal Small Intestine
PurposeTo investigate the gastrointestinal secretory and enzymatic responses to a liquid meal during in vivo perfusion of the… 
1997
1997
Fluorescent bile acid derivatives: Relationship between chemical structure and hepatic and intestinal transport in the rat
Studies were performed to characterize hepatic and intestinal transport, as well as biotransformation during transport, of a… 
Highly Cited
1983
Highly Cited
1983
Strain differences in mice in carbon tetrachloride-induced liver injury.
A study was made in inbred mice of genetic determinants of toxic liver cell injury, and the subsequent occurrence of… 
Highly Cited
1982
Highly Cited
1982
Bile salt metabolism in the first year of life.
Bile salt metabolism was examined in 12 infants (ages 7 weeks to 10 months) who had recovered from protracted infantile diarrhea… 
Highly Cited
1981
Highly Cited
1981
Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants.
Immaturity of hepatic excretory function resulting in a period of "physiologic cholestasis" may occur during early life. Serum… 
Highly Cited
1979
Highly Cited
1979
Determination of bile acids in serum by capillary gas-liquid chromatography.
1975
1975
Development of an intravenous bile acid tolerance test. Plasma disappearance of cholylglycine in health.
To develop an intravenous bile acid tolerance test that might be useful for detecting impaired liver function or liver injury… 
Highly Cited
1974
Highly Cited
1974
The preparation and properties of an antiserum for the radioimmunoassay of serum conjugated cholic acid.
Highly Cited
1972
Highly Cited
1972
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. I. Cholylglycine.
Cholyl-2,4-(3)H-glycine-1-(14)C was administered orally to eight healthy subjects with indwelling nasoduodenal tubes. The… 
Highly Cited
1972
Highly Cited
1972
Bile acid metabolism in mammals. 3. Sex difference in the bile acid composition of rat bile.
Bile was collected from 12 rats, six of each sex, for the first 5 h following the creation of a biliary fistula. The bile acid… 
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