cholate

Known as: 3alpha,7alpha,12alpha-Trihydroxy-5beta-Cholan-24-Oate, 3alpha,7alpha,12alpha-Trihydroxy-5beta-Cholanate 
An ester or salt of the bile acid cholic acid that is synthesized in the liver from cholesterol, with surfactant and signaling activities in the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Spore formation by Clostridium difficile is a significant obstacle to overcoming hospital-acquired C. difficile-associated… (More)
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2007
2007
Nanodiscs are protein-lipid particles that furnish a nanometer-sized membrane environment for the investigation of membrane… (More)
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Review
2006
Review
2006
Lipid-enriched diets are often used to induce or accelerate the rate of atherosclerotic lesion development in murine models of… (More)
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Highly Cited
2004
Highly Cited
2004
Niemann-Pick C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal cholesterol… (More)
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Highly Cited
2004
Highly Cited
2004
Activation of the 5-lipoxygenase (5-LO) pathway leads to the biosynthesis of proinflammatory leukotriene lipid mediators. Genetic… (More)
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Highly Cited
2003
Highly Cited
2003
The bile salt-activated farnesoid X receptor (FXR; NR1H4) controls expression of several genes considered crucial in maintenance… (More)
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Highly Cited
1999
Highly Cited
1999
A 5.9-kb region of the Bacillus subtilis chromosome is transcribed as a single transcript that is predicted to encode seven… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS The mouse mdr2 gene encodes a P-glycoprotein expressed in the hepatocanalicular membrane. Inactivation of this… (More)
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Highly Cited
1994
Highly Cited
1994
Using expression cloning in Xenopus laevis oocytes, we have isolated a cDNA encoding a rat liver organic anion-transporting… (More)
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Highly Cited
1984
Highly Cited
1984
Membranes from bovine brain bind relatively large quantities of guanosine 5'-(3-O-thio)triphosphate (GTP gamma S) with high… (More)
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