Cholic Acid

Known as: acid cholic, Cholan-24-oic acid, 3,7,12-trihydroxy-, (3-alpha, 5-beta, 7-alpha, 12-alpha)-, Acid, Cholic 
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1937-2018
05010019372017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Bile acids are synthesized from cholesterol in the liver and further metabolized by the gut microbiota into secondary bile acids… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Alterations in the gastrointestinal microbiota have been associated with metabolic diseases. However, little is… (More)
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Highly Cited
2009
Highly Cited
2009
TGR5 is a G protein-coupled receptor expressed in brown adipose tissue and muscle, where its activation by bile acids triggers an… (More)
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Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… (More)
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Highly Cited
2007
Highly Cited
2007
Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear hormone receptor superfamily, which plays an essential role in… (More)
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Highly Cited
2004
Highly Cited
2004
We explored the effects of bile acids on triglyceride (TG) homeostasis using a combination of molecular, cellular, and animal… (More)
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Highly Cited
2003
Highly Cited
2003
The ileal apical sodium bile acid cotransporter participates in the enterohepatic circulation of bile acids. In patients with… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND AIMS Cholestasis is associated with retention of potentially toxic bile acids and alterations in hepatocellular… (More)
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Highly Cited
1989
Highly Cited
1989
The conversion of cholesterol into bile acids in the liver represents the major catabolic pathway for the removal of cholesterol… (More)
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Highly Cited
1987
Highly Cited
1987
The well-defined genetic systems of the mouse are proving useful in experimental studies of atherosclerosis. Inbred mouse strains… (More)
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