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Cholic Acid

Known as: acid cholic, Cholan-24-oic acid, 3,7,12-trihydroxy-, (3-alpha, 5-beta, 7-alpha, 12-alpha)-, Acid, Cholic 
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Once known exclusively for their role in nutrients absorption, primary bile acids, chenodeoxycholic and cholic acid, and… Expand
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Highly Cited
2013
Highly Cited
2013
Bile acids are synthesized from cholesterol in the liver and further metabolized by the gut microbiota into secondary bile acids… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Alterations in the gastrointestinal microbiota have been associated with metabolic diseases. However, little is… Expand
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Highly Cited
2009
Highly Cited
2009
TGR5 is a G protein-coupled receptor expressed in brown adipose tissue and muscle, where its activation by bile acids triggers an… Expand
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Highly Cited
2004
Highly Cited
2004
We explored the effects of bile acids on triglyceride (TG) homeostasis using a combination of molecular, cellular, and animal… Expand
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Highly Cited
2004
Highly Cited
2004
We now report metal-free organic dyes having a new type of indoline structure, which exhibits high efficiencies in dye-sensitized… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND AIMS Cholestasis is associated with retention of potentially toxic bile acids and alterations in hepatocellular… Expand
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Highly Cited
1994
Highly Cited
1994
Mice that are homozygous for a targeted disruption of the LDL receptor gene (LDLR-/- mice) were fed a diet that contained 1.25… Expand
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Highly Cited
1989
Highly Cited
1989
The conversion of cholesterol into bile acids in the liver represents the major catabolic pathway for the removal of cholesterol… Expand
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Highly Cited
1987
Highly Cited
1987
The well-defined genetic systems of the mouse are proving useful in experimental studies of atherosclerosis. Inbred mouse strains… Expand
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