Deoxycholic Acid

Known as: Desoxycholic Acid, Acid, Desoxycholic, Cholan-24-oic acid, 3,12-dihydroxy-, (3alpha,5beta,12alpha)- 
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Obesity has become more prevalent in most developed countries over the past few decades, and is increasingly recognized as a… (More)
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Highly Cited
2012
Highly Cited
2012
A targeted intracellular delivery system of paclitaxel (PTX) was successfully developed based on redox-sensitive hyaluronic acid… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Alterations in the gastrointestinal microbiota have been associated with metabolic diseases. However, little is… (More)
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Highly Cited
2011
Highly Cited
2011
High dietary fat causes increased bile acid secretion into the gastrointestinal tract and is associated with colon cancer. Since… (More)
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Highly Cited
2001
Highly Cited
2001
Previous studies have argued that enhanced activity of the epidermal growth factor receptor (EGFR) and the mitogen-activated… (More)
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Highly Cited
1999
Highly Cited
1999
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Hyperproliferation of the colorectal mucosa is regarded as an early step in colorectal carcinogenesis. Deoxycholic… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The hydrophilic bile salt ursodeoxycholate (UDCA) inhibits injury by hydrophobic bile acids and is used to treat… (More)
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Highly Cited
1998
Highly Cited
1998
The hydrophilic bile salt ursodeoxycholic acid (UDCA) protects against the membrane-damaging effects associated with hydrophobic… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Epidemiological and animal studies have suggested that the secondary bile acid deoxycholic acid is cocarcinogenic in… (More)
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