Chenodeoxycholic Acid

Known as: Chenocholic acid, Chenodesoxycholic acid, Chenodiol 
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND & AIMS Obeticholic acid (OCA; INT-747, 6α-ethyl-chenodeoxycholic acid) is a semisynthetic derivative of the primary… (More)
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Highly Cited
2010
Highly Cited
2010
To cause disease, Clostridium difficile spores must germinate in the host gastrointestinal tract. Germination is initiated upon… (More)
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Highly Cited
2010
Highly Cited
2010
The effect of chemical modification of mesoporous TiO2 electrodes by 2-(4-butoxyphenyl)-N-hydroxyacetamide (BPHA) before dye… (More)
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Highly Cited
2002
Highly Cited
2002
A series of 6alpha-alkyl-substituted analogues of chenodeoxycholic acid (CDCA) were synthesized and evaluated as potential… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
1999
Highly Cited
1999
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly… (More)
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Highly Cited
1999
Highly Cited
1999
The major metabolic pathway for elimination of cholesterol is via conversion to bile acids. In addition to this metabolic… (More)
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Highly Cited
1993
Highly Cited
1993
How lipophilic acids move across membranes, either model or biological, is the subject of controversy. We describe experiments… (More)
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Highly Cited
1989
Highly Cited
1989
The conversion of cholesterol into bile acids in the liver represents the major catabolic pathway for the removal of cholesterol… (More)
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Highly Cited
1984
Highly Cited
1984
We studied the effect of chenodeoxycholic acid in 17 patients with cerebrotendinous xanthomatosis. Before treatment, all subjects… (More)
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