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Chenodeoxycholic Acid

Known as: Chenocholic acid, Chenodesoxycholic acid, Chenodiol 
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
ABSTRACT To cause disease, Clostridium difficile spores must germinate in the host gastrointestinal tract. Germination is… Expand
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Highly Cited
2008
Highly Cited
2008
Carbonic anhydrase, a zinc enzyme found in organisms from all kingdoms, catalyses the reversible hydration of carbon dioxide and… Expand
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Highly Cited
2002
Highly Cited
2002
A series of 6alpha-alkyl-substituted analogues of chenodeoxycholic acid (CDCA) were synthesized and evaluated as potential… Expand
Highly Cited
1999
Highly Cited
1999
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly… Expand
Highly Cited
1999
Highly Cited
1999
The major metabolic pathway for elimination of cholesterol is via conversion to bile acids. In addition to this metabolic… Expand
Highly Cited
1989
Highly Cited
1989
The conversion of cholesterol into bile acids in the liver represents the major catabolic pathway for the removal of cholesterol… Expand
Highly Cited
1984
Highly Cited
1984
We studied the effect of chenodeoxycholic acid in 17 patients with cerebrotendinous xanthomatosis. Before treatment, all subjects… Expand
Review
1981
Review
1981
A double-masked study was conducted to determine the efficacy and safety of randomly allocated chenodiol (chenodeoxycholic acid… Expand
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Review
1978
Review
1978
RECEIVED for review February 21, 1978. Accepted June 19, 1978. NMR spectra since two distinct peaks (6 -3.38, 3.78 ppm) caused by… Expand
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Highly Cited
1972
Highly Cited
1972
Abstract Seven women with gallstones were given 0.75 to 4.5 g per day of chenodeoxycholic acid, a primary bile acid, to promote… Expand