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Chenodeoxycholic Acid

Known as: Chenocholic acid, Chenodesoxycholic acid, Chenodiol 
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (21)

23-hydroxychenodeoxycholic acid23-norchenodeoxycholic acid24-norchenodeoxycholic acid3,7-dihydroxy-12-oxocholanoic acid

Broader (4)

Bile Acids and SaltsCatharticsDeoxycholic AcidGastrointestinal Agents
Drug AllergyIn BloodLiver diseasesPancreatitis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
An alternative approach based on microfluidics to study drug metabolism and toxicity using liver and intestinal tissue
Microfluidic technologies enable the fabrication of advanced in vitro systems incorporating liver tissue or cells to perform… 
Highly Cited
1984
Highly Cited
1984
Effect of Ursodeoxycholic Acid on Biliary Bile Acid and Bile Lipid Composition in Gallstone Patients
In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250, 500, 750, 1,000, and 1… 
Highly Cited
1982
Highly Cited
1982
Pretreatment biliary lipid composition in white patients with radiolucent gallstones in the National Cooperative Gallstone Study.
Highly Cited
1982
Highly Cited
1982
Bioluminescence measurement of primary bile acids using immobilized 7 alpha-hydroxysteroid dehydrogenase: application to serum bile acids.
A simple, rapid, and sensitive bioluminescence method for measuring primary bile acids has been developed and validated. The… 
Highly Cited
1980
Highly Cited
1980
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids.
To define the metabolism of 7-ketolithocholic acid in man, studies were carried out in gallstone patients with normal liver… 
Highly Cited
1976
Highly Cited
1976
Impaired lithocholate sulfation in the rhesus monkey: a possible mechanism for chenodeoxycholate toxicity.
Highly Cited
1975
Highly Cited
1975
Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients.
Bile acid kinetics were measured by isotope dilution, and hourly outputs of bile acid, cholesterol, and phospholipid were… 
Highly Cited
1974
Highly Cited
1974
Quantitative analysis of bile acids in serum and bile, using gas--liquid chromatography.
Highly Cited
1970
Highly Cited
1970
Quantitative determination of the major 3-hydroxy bile acids in biological material after thin-layer chromatographic separation.
  • A. Bruusgaard
  • Clinica chimica acta; international journal of…
  • 1970
  • Corpus ID: 35789779
Review
1964
Review
1964
THE BIOLOGICAL SIGNIFICANCE OF CHEMICAL DIFFERENCES IN BILE SALTS
1. The chemical nature of the bile salts is a character that must be under the control of several genes and is also affected by… 
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