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Chenodeoxycholic Acid
Known as:
Chenocholic acid
, Chenodesoxycholic acid
, Chenodiol
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A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed…
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National Institutes of Health
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Related topics
Related topics
37 relations
Narrower (21)
23-hydroxychenodeoxycholic acid
23-norchenodeoxycholic acid
24-norchenodeoxycholic acid
3,7-dihydroxy-12-oxocholanoic acid
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Broader (4)
Bile Acids and Salts
Cathartics
Deoxycholic Acid
Gastrointestinal Agents
Drug Allergy
In Blood
Liver diseases
Pancreatitis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Consequences of bile salt biotransformations by intestinal bacteria
J. Ridlon
,
Spencer C. Harris
,
S. Bhowmik
,
Daejoong Kang
,
P. Hylemon
Gut microbes
2016
Corpus ID: 43028932
ABSTRACT Emerging evidence strongly suggest that the human “microbiome” plays an important role in both health and disease. Bile…
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Highly Cited
2013
Highly Cited
2013
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.
G. Kakiyama
,
W. Pandak
,
+14 authors
J. Bajaj
Journal of Hepatology
2013
Corpus ID: 28051428
Highly Cited
2010
Highly Cited
2010
Inhibiting the Initiation of Clostridium difficile Spore Germination using Analogs of Chenodeoxycholic Acid, a Bile Acid
Joseph A. Sorg
,
A. Sonenshein
Journal of Bacteriology
2010
Corpus ID: 13790232
ABSTRACT To cause disease, Clostridium difficile spores must germinate in the host gastrointestinal tract. Germination is…
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Highly Cited
2008
Highly Cited
2008
Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms
Yan Xu
,
Liang Feng
,
P. Jeffrey
,
Yigong Shi
,
F. Morel
Nature
2008
Corpus ID: 4420280
Carbonic anhydrase, a zinc enzyme found in organisms from all kingdoms, catalyses the reversible hydration of carbon dioxide and…
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Highly Cited
2002
Highly Cited
2002
6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.
R. Pellicciari
,
S. Fiorucci
,
+6 authors
T. Willson
Journal of Medicinal Chemistry
2002
Corpus ID: 19573619
A series of 6alpha-alkyl-substituted analogues of chenodeoxycholic acid (CDCA) were synthesized and evaluated as potential…
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Highly Cited
1999
Highly Cited
1999
Bile acids: natural ligands for an orphan nuclear receptor.
D. Parks
,
S. Blanchard
,
+8 authors
J. Lehmann
Science
1999
Corpus ID: 36889513
Bile acids regulate the transcription of genes that control cholesterol homeostasis through molecular mechanisms that are poorly…
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Highly Cited
1999
Highly Cited
1999
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.
H. Wang
,
J. Chen
,
K. Hollister
,
L. Sowers
,
B. M. Forman
Molecules and Cells
1999
Corpus ID: 43157350
Highly Cited
1989
Highly Cited
1989
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme.
S. Andersson
,
D. L. Davis
,
H. Dahlbäck
,
H. Jörnvall
,
D. Russell
Journal of Biological Chemistry
1989
Corpus ID: 26421822
Highly Cited
1984
Highly Cited
1984
Long-term treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid.
V. Berginer
,
G. Salen
,
S. Shefer
New England Journal of Medicine
1984
Corpus ID: 34117319
We studied the effect of chenodeoxycholic acid in 17 patients with cerebrotendinous xanthomatosis. Before treatment, all subjects…
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Highly Cited
1972
Highly Cited
1972
Dissolution of cholesterol gallstones by chenodeoxycholic acid.
R. Danzinger
,
A. Hofmann
,
L. Schoenfield
,
J. Thistle
New England Journal of Medicine
1972
Corpus ID: 20019501
Abstract Seven women with gallstones were given 0.75 to 4.5 g per day of chenodeoxycholic acid, a primary bile acid, to promote…
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