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3,7-dihydroxy-12-oxocholanoic acid

Known as: 12-ketochenodeoxycholic acid, 12-oxo-3,7-dihydroxycholanoic acid, cholan-24-oic acid, 3,7-dihydroxy-12-oxo-, (3 alpha,5 beta,7 alpha)- 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Chenodeoxycholic Acid
analogs & derivatives

Narrower (1)

sodium monoketocholate

Papers overview

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2011
2011
In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum
Nicotinamide adenine dinucleotide phosphate-dependent 7α-hydroxysteroid dehydrogenase (7α-HSDH) and 7β-hydroxysteroid… Expand
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2011
2011
Biocatalytic process optimization based on mechanistic modeling of cholic acid oxidation with cofactor regeneration.
Reduction and oxidation of steroids in the human gut are catalyzed by hydroxysteroid dehydrogenases of microorganisms. For the… Expand
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2006
2006
Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid.
The performance of a new NADP-regeneration system, based on the use of alcohol dehydrogenase (ADH)-acetone, has been investigated… Expand
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1990
1990
Identification of short side chain bile acids in urine of patients with cerebrotendinous xanthomatosis.
Urine from patients with cerebrotendinous xanthomatosis (CTX) was found to contain a number of minor bile acids along with three… Expand
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1987
1987
Enzymes involved in the formation of 3 beta, 7 beta-dihydroxy-12-oxo-5 beta-cholanic acid from dehydrocholic acid by Ruminococcus sp. obtained from human intestine.
Ruminococcus sp. PO1-3 from human intestinal flora reduced dehydrocholic acid to 3 beta-hydroxy-7,12-dioxo-5 beta-cholanic acid… Expand
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1984
1984
Enzymatic preparation of 12-ketochenodeoxycholic acid with NADP regeneration.
Preparation de ce compose d'interet pharamceutique pour la synthese de l'acide chenodesoxycholique, en utilisant l'oxydation… Expand
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1981
1981
Continuous production of 12-ketochenodeoxycholic acid in a column reactor containing immobilized living cells of Brevibacterium fuscum
 
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1980
1980
Microbial production of chenodeoxycholic acid precursor, 12-ketochenodeoxycholic acid, from dehydrocholic acid
SummaryTwo kinds of bacteria (DC33 and DC1115) were isolated from soil as biotransformers of dehydrocholic acid to 12… Expand
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1972
1972
The metabolic sequence for the occurrence of an anomalous bile acid, 12-ketochenodeoxycholic acid, found in the bile of hepatobiliary diseased patients.
 
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1972
1972
The metabolic sequence for the occurrence of an anomalous bile acid, 12-ketochenodeoxycholic acid, found in the bile of hepatobiliary diseased patients
 
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