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Natural occurrence and chemical synthesis of bile alcohols, higher bile acids, and short side chain bile acids.
TLDR
Although the distribution of bile alcohols and higher bile acids in nature was long considered to be confined to the primitive vertebrates, it is now recognized that these compounds are accummulated in patients with inherited diseases related to abnormal cholesterol metabolism.
Hyperbilirubinemia of Coho Salmon Oncorhynchus kisutch Infected with Erythrocytic Inclusion Body Syndrome (EIBS) Virus
TLDR
This paper aims to provide a history of Freshwater Fisheries Experimental Station experiments in Japan from 1989 to 1994 and aims to establish a chronology of events leading to and including the establishment of the Miyagi Freshwater Fisheries Experimental Station.
Bacterial 7-dehydroxylation of cholic acid and allocholic acid.
TLDR
The existence of this organism affords a satisfactory explanation for the development of gallstones in the cholestanol-fed rabbit and for their absence in rabbits simultaneously treated with neomycin.
A point mutation in the bile acid biosynthetic enzyme sterol 27-hydroxylase in a family with cerebrotendinous xanthomatosis.
TLDR
An increase in plasma cholestanol alone would not appear to be a direct cause of sterol storage in CTX, while CTX is strongly suggested to be caused by defects in both alleles of the CYP27 gene.
Purification and characterization of phospholipase A2 from the pyloric caeca of red sea bream, Pagrus major
A phospholipase A2 was purified 55,000-fold in a yield of 10% from the lipid-free extract of powder of the pyloric caeca of red sea bream to near homogeneity by sequential column chromatography on
Effects of dietary konjac mannan on serum and liver cholesterol levels and biliary bile acid composition in hamsters.
TLDR
The increase in the proportion of chenodeoxycholic acid in biliary bile acids was significantly enhanced in the hamsters feeding both cholesterol and konjac mannan compared to hamsters fed the control diet, which may suggest that konJac mannan inhibits the intestinal absorption of bile acid.
Comparison of side chain oxidation of potential C27-bile acid intermediates between mitochondria and peroxisomes of the rat liver: presence of beta-oxidation activity for bile acid biosynthesis in
TLDR
The results strongly suggest that the cleavage of the side chain of the C27-intermediates for bile acid biosynthesis also occurs independently in the mitochondria, not due to the contamination of peroxisomes.
Isolation of two bile acids from bile of eel.
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