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Malignancy in coeliac disease--effect of a gluten free diet.
The results indicate that for coeliac patients who have taken a GFD for five years or more the risk of developing cancer over all sites is not increased when compared with the general population, and give further support for advising all patients to adhere to a strict G FD for life.
Risk factors for intra-abdominal sepsis after surgery in Crohn's disease
Preoperative low albumin level, steroid use, and the presence of abscess or fistula at the time of laparotomy significantly increased the risk of septic complications after surgery in Crohn's disease.
Ulcerative colitis and Crohn's disease: a comparison of the colorectal cancer risk in extensive colitis.
There was an 18-fold increase in the risk of developing colorectal cancer in extensive Crohn's colitis and a 19-fold increased in risk in extensive ulcerative colitis when compared with the general population, matched for age, sex, and years at risk.
Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres.
It is suggested that extensive colitis patients have a genetic predisposition to colorectal cancer and that longstanding inflammation is not of primary importance in the initiation/promotion of cancer in this disease.
Current status and influence of operation on perianal Crohn's disease
The results imply that patients with perianal Crohn's disease should be treated conservatively and that proctectomy, particularly in patients with rectal strictures, is associated with very high incidence of persistent perineal sinus.
Malignancy in Crohn's disease.
- S. Gyde, P. Prior, J. Macartney, H. Thompson, J. Waterhouse, R. Allan
- MedicineBritish journal of preventive & social medicine
- 1 December 1980
Cancer morbidity has been evaluated in a series of 513 patients with Crohn's disease under long-term review between 1944-76 and there was no excess of tumours at any site outside the digestive system.
Psychiatric illness in patients with inflammatory bowel disease.
Patients attending a clinic for inflammatory bowel disease were assessed for the presence of anxiety and depression using a simple self-rating questionnaire (HAD scale) and a detailed evaluation (DSM-III).
Cancer morbidity in ulcerative colitis.
The pattern of risk of colorectal cancer over time suggests that there is an association between cancer and colitis in susceptible individuals and that the level of risk is related to age at onset of colitis.
Biliary tract carcinoma associated with ulcerative colitis.
- J. Ritchie, R. Allan, J. Macartney, H. Thompson, P. Hawley, W. Cooke
- MedicineThe Quarterly journal of medicine
- 1 April 1974
This paper reports 15 well-documented cases in which a biliary tract tumour has developed in a patient with ulcerative colitis, suggesting that these tumours are approximately 10 times more frequent in patients with ulcers than in the general population.
An audit of strictureplasty for small-bowel crohn's disease
Strictureplasty is a safe and efficacious procedure for small-bowel Crohn's disease in the long-term, and the majority of patients with preoperative weight loss gained weight.