S. Grundy

Publications1,023
h-index186
Citations215,895
Highly Influential Citations5,649
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Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American…
TLDR
It was agreed that there should not be an obligatory component, but that waist measurement would continue to be a useful preliminary screening tool, and a single set of cut points would be used for all components except waist circumference, for which further work is required. Expand
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement.
TLDR
This statement from the American Heart Association and the National Heart, Lung, and Blood Institute is intended to provide up-to-date guidance for professionals on the diagnosis and management of the metabolic syndrome in adults. Expand
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines.
TLDR
The trials confirm the benefit of cholesterol-lowering therapy in high-risk patients and support the ATP III treatment goal of low-density lipoprotein cholesterol (LDL-C) <100 mg/dL, and confirm that older persons benefit from therapeutic lowering of LDL-C. Expand
Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition
TLDR
Although ATP III identified CVD as the primary clinical outcome of the metabolic syndrome, most people with this syndrome have insulin resistance, which confers increased risk for type 2 diabetes, when diabetes becomes clinically apparent, CVD risk rises sharply. Expand
Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
TLDR
The trials confirm the benefit of cholesterol-lowering therapy in high-risk patients and support the ATP III treatment goal of low-density lipoprotein cholesterol (LDL-C) <100 mg/dL, and confirm that older persons benefit from therapeutic lowering of LDL-C. Expand
Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
TLDR
The prevalence of hepatic steatosis was greater in men than women among whites, but not in blacks or Hispanics, and significant ethnic and sex differences in the prevalence may have a profound impact on susceptibility to Steatosis‐related liver disease. Expand
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment…
THE THIRD REPORT OF THE EXpert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III, or ATP III) constitutes the National Cholesterol Education… Expand
Metabolic Syndrome Pandemic
  • S. Grundy
  • Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 April 2008
TLDR
This review addresses the prevalence of this clustering phenomenon throughout the world and focuses attention on obesity and sedentary life habits that are the root of the syndrome. Expand
The metabolic syndrome
TLDR
The metabolic syndrome is a master of disguise since it can present in various ways according to the different components that constitute the syndrome and Lemieux and colleagues have suggested the importance of abdominal obesity and the so-called hypertriglyceridaemic waist phenotype as a central component. Expand
Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults.
TLDR
The aim of this guideline is to provide useful advice on how to achieve weight reduction and maintenance of a lower body weight and to note that prevention of further weight gain can be a goal for some patients. Expand
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