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Geranyltranstransferase

Known as: FPP Synthetase, Farnesyl Diphosphate Synthase, Diphosphate Synthase, Farnesyl 
An enzyme involved in the MEVALONATE pathway, it catalyses the synthesis of farnesyl diphosphate from isopentenyl diphosphate and dimethylallyl… 
National Institutes of Health

Related topics

Related topics

13 relations
DimethylallyltranstransferaseFDPS geneIn BloodProcess of secretion

Narrower (3)

Farnesyl Pyrophosphate Synthetase, humanIspA protein, E colichrysanthemyl diphosphate synthase, Chrysanthemum

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Characterization and functional analysis of cis-acting elements of the human farnesyl diphosphate synthetase (FDPS) gene 5' flanking region.
1997
1997
Synthesis of characteristic lipopeptides of the human N-Ras protein and their evaluation as possible inhibitors of protein farnesyl transferase.
1994
1994
Photoaffinity-labeling peptide substrates for farnesyl-protein transferase and the intersubunit location of the active site.
Highly Cited
1993
Highly Cited
1993
Biosynthesis of ubiquinone and plastoquinone in the endoplasmic reticulum-Golgi membranes of spinach leaves.
Highly Cited
1991
Highly Cited
1991
Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels.
1991
1991
Biosynthesis of membrane-derived oligosaccharides. Membrane-bound glucosyltransferase system from Escherichia coli requires polyprenyl phosphate.
The periplasmic glucans of Gram-negative bacteria, including the membrane-derived oligosaccharides (MDO) of Escherichia coli and… 
Highly Cited
1989
Highly Cited
1989
Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells.
A partial length cDNA encoding farnesyl pyrophosphate synthetase (hpt807) has been isolated from a human fetal liver cDNA library… 
1985
1985
Isoprenoid enzyme systems of silkworm. I. Partial purification of isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase.
Isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase were detected… 
1971
1971
Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations.
Highly Cited
1966
Highly Cited
1966
Sites of control of hepatic cholesterol biosynthesis.
An inhibition in the conversion of mevalonate to cholesterol has been demonstrated in liver of cholesterol-fed rats by both in… 
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