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Farnesyl Pyrophosphate Synthetase, human

Known as: FPP Synthetase, (2E,6E)-Farnesyl Diphosphate Synthase, Farnesyl Diphosphate Synthase 
Farnesyl pyrophosphate synthase (419 aa, ~48 kDa) is encoded by the human FDPS gene. This protein plays a role in the synthesis of geranyl… 
National Institutes of Health

Related topics

Related topics

5 relations
Enzyme GeneFDPS geneLipid MetabolismTerpenoid Biosynthesis Pathway

Broader (1)

Geranyltranstransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase from Trypanosoma brucei.
Farnesyl diphosphate synthase (FPPS) catalyses the formation of farnesyl diphosphate from dimethylallyl diphosphate and… 
2002
2002
Partial purification of a farnesyl diphosphate synthase from whole-body Manduca sexta.
Highly Cited
1997
Highly Cited
1997
Conversion from Archaeal Geranylgeranyl Diphosphate Synthase to Farnesyl Diphosphate Synthase
Farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP) are precursors for a variety of important natural products, such… 
1995
1995
Farnesyl pyrophosphate synthase from white lupin: molecular cloning, expression, and purification of the expressed protein.
Plants produce a variety of sesquiterpenoid compounds with diverse biological functions, whose synthesis is initiated by farnesyl… 
1995
1995
Significance of Phe-220 and Gln-221 in the catalytic mechanism of farnesyl diphosphate synthase of Bacillus stearothermophilus.
Farnesyl diphosphate synthase [EC 2.5.1.10] from Bacillus stearothermophilus was specifically altered at two amino acid residues… 
Highly Cited
1990
Highly Cited
1990
Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase…
Highly Cited
1989
Highly Cited
1989
Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells.
A partial length cDNA encoding farnesyl pyrophosphate synthetase (hpt807) has been isolated from a human fetal liver cDNA library… 
1986
1986
Biosynthesis of the Macrocyclic Diterpene Casbene in Castor Bean (Ricinus communis L.) Seedlings : Changes in Enzyme Levels Induced by Fungal Infection and Intracellular Localization of the Pathway.
Casbene is a macrocyclic diterpene hydrocarbon that is produced in young castor bean (Ricinus communis L.) seedlings after they… 
1985
1985
Isoprenoid enzyme systems of silkworm. I. Partial purification of isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase.
Isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase were detected… 
1977
1977
Two forms of farnesyl pyrophosphate synthetase from hog liver.
Two forms of farnesyl pyrophosphate synthetase were separated from hog liver extracts by DEAE-Sephadex chromatography. They were… 
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