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Biogeochemistry of Microbial Coal-Bed Methane
TLDR
The anaerobic metabolism of the bacteria breaking coal down to methanogenic substrates, the likely rate-limiting step in biogenic gas production, is not fully understood and coal molecules are more recalcitrant to biodegradation with increasing thermal m... Expand
Modulation of Ras and a-Factor Function by Carboxyl-Terminal Proteolysis
TLDR
Two genes in Saccharomyces cerevisiae, RCE1 and AFC1, were identified that appear to be responsible for the processing of prenylated proteins, which contain a covalently linked cholesterol intermediate near their carboxyl-termini. Expand
Role of Yeast Insulin-Degrading Enzyme Homologs in Propheromone Processing and Bud Site Selection
TLDR
The Saccharomyces cerevisiae AXL1 gene product Axl1p has been shown to participate in the dual regulation of distinct signaling pathways, and a member of the insulinase family has been implicated in propeptide processing. Expand
COQ2 is a candidate for the structural gene encoding para-hydroxybenzoate:polyprenyltransferase.
TLDR
Disruption of the chromosomal COQ2 gene indicates the gene is not essential for viability, yet is required for PHB:polyprenyltransferase activity and respiratory function, and the deduced amino acid sequence ofPHB: PolyPrenyl transferase contains a putative allylic polypreny diphosphate-binding site. Expand
Serial Analysis of rRNA Genes and the Unexpected Dominance of Rare Members of Microbial Communities
TLDR
The large numbers of singleton tags indicated that a significant amount of sequence tag diversity remained undetected with this level of sampling, and taxa with low abundance comprised a significant proportion of the microbial communities examined and could potentially make a large contribution to ecosystem function. Expand
Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase.
TLDR
The hydrophobicity correlation coefficient of the comparison of these two sequences indicate with a high degree of confidence that the two proteins will fold into similar three-dimensional structures. Expand
Disruption of the Mouse Rce1 Gene Results in Defective Ras Processing and Mislocalization of Ras within Cells*
TLDR
These studies indicate that Rce1 is responsible for the endoproteolytic processing of the Ras proteins in mammals and suggest a broad role for this gene in processing other prenylated CAAX proteins. Expand
Microbialite genetic diversity and composition relate to environmental variables.
TLDR
Analysis of genetic genetic diversity of microbialites living in different types of environments throughout Mexico showed that microbialite communities were very diverse and showed geographic variation in composition, as well as an environmental effect related to pH and conductivity, which together explained 33% of the genetic variation. Expand
Biochemical Studies of Zmpste24-deficient Mice*
TLDR
Both enzymatic activities of yeast Ste24p are conserved in mouse Zmpste24, but these enzymatics activities are not essential for mouse development or for fertility. Expand
Biogeochemistry of Microbial CoalBed Methane
1ConocoPhillips, Houston, Texas 77079 2Indiana Geological Survey, Indiana University, Bloomington, Indiana 47405 3Geosciences Department, Pennsylvania State University, University Park, PennsylvaniaExpand
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