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Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand We isolated the human adipose-specific and most abundant gene transcript, apM1 (Maeda, K., et al., Biochem. Biophys. Res. Commun… Expand Hypoxia-inducible factor-1 (HIF-1) has a key role in cellular responses to hypoxia, including the regulation of genes involved in… Expand The human homologue of Drosophila Toll (hToll), also called Toll-like receptor 4 (TLR4), is a recently cloned receptor of the IL… Expand A new gene, termed klotho, has been identified that is involved in the suppression of several ageing phenotypes. A defect in… Expand The gene product of the ob locus is important in the regulation of body weight. The ob product was shown to be present as a 16… Expand The recent positional cloning of the mouse ob gene and its human homology has provided the basis to investigate the potential… Expand Amorphous metal alloys are employed in acoustic devices dependent upon the properties of low acoustic velocity and low… Expand A gene discovered by positional cloning has been identified as the von Hippel-Lindau (VHL) disease tumor suppressor gene. A… Expand Deletions or mutations of the retinoblastoma gene, RB1, are common features of many tumors and tumor cell lines. Recently, the… Expand