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Genistein
Known as:
Prunetol
, Genisteol
, Genisterin
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A soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting…
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National Institutes of Health
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Related topics
Related topics
35 relations
Narrower (14)
3',8-dichlorogenistein
4'-amino-6-hydroxyflavone
6,8-diprenylgenistein
6-carboxymethyl genistein
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Broader (5)
Anticarcinogenic Agents
Flavones
Isoflavones
Phytoestrogens
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Antineoplastic Agents
B43-genistein immunoconjugate
Chemoprevention
Estrogens, Synthetic
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Multi-targeted therapy of cancer by genistein.
Sanjeev Banerjee
,
Yiwei Li
,
Zhiwei Wang
,
F. Sarkar
Cancer Letters
2008
Corpus ID: 21458670
Highly Cited
2006
Highly Cited
2006
Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome
D. Dolinoy
,
J. Weidman
,
R. Waterland
,
R. Jirtle
Environmental Health Perspectives
2006
Corpus ID: 18818397
Genistein, the major phytoestrogen in soy, is linked to diminished female reproductive performance and to cancer chemoprevention…
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Review
2006
Review
2006
Molecular targets of dietary agents for prevention and therapy of cancer.
B. Aggarwal
,
S. Shishodia
Biochemical Pharmacology
2006
Corpus ID: 13890326
Highly Cited
1996
Highly Cited
1996
Molecular effects of genistein on estrogen receptor mediated pathways.
Thomas T. Y. Wang
,
N. Sathyamoorthy
,
J. Phang
Carcinogenesis
1996
Corpus ID: 24701843
Genistein, a component of soy products, may play a role in the prevention of breast and prostate cancer. However, little is known…
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Highly Cited
1995
Highly Cited
1995
Antioxidant and Antipromotional Effects of the Soybean Isoflavone Genistein
Huachen Wei
,
Ronald Bowen
,
Q. Cai
,
S. Barnes
,
Yan Wang
Proceedings of the Society for Experimental…
1995
Corpus ID: 33542277
Abstract Antioxidant and antipromotional effects of the soybean isoflavone genistein have been studied in HL-60 cells and the…
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Review
1995
Review
1995
Effect of genistein on in vitro and in vivo models of cancer.
S. Barnes
Journal of NutriLife
1995
Corpus ID: 19047978
In two-thirds of studies on the effect of genistein-containing soy materials in animal models of cancer, the risk of cancer…
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Highly Cited
1994
Highly Cited
1994
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).
C. Vlahos
,
W. Matter
,
K. Hui
,
R. F. Brown
Journal of Biological Chemistry
1994
Corpus ID: 19752008
Highly Cited
1993
Highly Cited
1993
Genistein, a dietary-derived inhibitor of in vitro angiogenesis.
T. Fotsis
,
M. Pepper
,
+4 authors
Lothar Schweigerer
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 39791502
Consumption of a plant-based diet can prevent the development and progression of chronic diseases that are associated with…
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Highly Cited
1989
Highly Cited
1989
Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II.
J. Markovits
,
C. Linassier
,
+6 authors
A. Larsen
Cancer Research
1989
Corpus ID: 23581915
Tyrosine phosphorylation plays a crucial role in cell proliferation and cell transformation which suggests that tyrosine kinase…
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Highly Cited
1987
Highly Cited
1987
Genistein, a specific inhibitor of tyrosine-specific protein kinases.
Tetsu AkiyamaSO
,
Junko IshidaST
,
+5 authors
Y. Fukami
Journal of Biological Chemistry
1987
Corpus ID: 24903943
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