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Gene Products, tax

Known as: Trans-Activator Protein p40(lor), p40x, Transforming Antigen, Trans-Activator Protein p40(tax) 
Transcriptional trans-acting proteins of the promoter elements found in the long terminal repeats (LTR) of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionTranscription, Geneticagonists

Broader (1)

Trans-Activators

Narrower (1)

tax2 protein, Human T-lymphotrophic virus 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein*
Background: Extracellular exosomes contain various functional elements. Results: Exosomal Tax protein causes phenotypic changes… 
Highly Cited
1996
Highly Cited
1996
Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB
In resting T lymphocytes, the transcription factor NF-kappaB is sequestered in the cytoplasm via interactions with members of the… 
Highly Cited
1996
Highly Cited
1996
Constitutive activation of NF‐kappa B is essential for transformation of rat fibroblasts by the human T‐cell leukemia virus type I Tax protein.
Human T‐cell leukemia virus type I (HTLV‐I) encodes a 40 kDa trans‐acting protein, Tax, that regulates transcription of both the… 
Highly Cited
1995
Highly Cited
1995
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
The human T-cell leukemia virus type I Tax protein trans-activates several cellular genes implicated in T-cell replication and… 
Highly Cited
1993
Highly Cited
1993
HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization.
The Tax protein of human T cell leukemia virus type-1 (HTLV-I) transcriptionally activates the HTLV-I promoter. This activation… 
Highly Cited
1992
Highly Cited
1992
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture
Human T-cell leukemia virus type 1 (HTLV-1) immortalizes human CD4+ T lymphocytes in culture. Previous studies show that in the… 
Highly Cited
1989
Highly Cited
1989
Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.
The human immunodeficiency virus (HIV-1)-encoded trans-activator (tat) increases HIV gene expression and replication. Previously… 
Highly Cited
1988
Highly Cited
1988
Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.
Expression of the interleukin-2 receptor (IL-2R alpha) gene is activated by the transcriptional activator protein, Tax… 
Highly Cited
1987
Highly Cited
1987
Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.
Cotransfection of cDNA encoding the trans-activator gene product of human T-cell leukemia virus, type I (HTLV-I) (tat-I), which… 
Highly Cited
1987
Highly Cited
1987
Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication.
Mutations were made by recombinant DNA techniques in an infectious molecular clone of the human immunodeficiency virus San… 
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