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Barriers to Antiretroviral Adherence for Patients Living with HIV Infection and AIDS in Botswana
- S. Weiser, W. Wolfe, R. Marlink
- Medicine, Political ScienceJournal of acquired immune deficiency syndromes
- 1 November 2003
ARV adherence rates in Botswana were comparable with those seen in developed countries, as health care providers were often unable to identify which patients adhere to their ARV regimens.
Prevention of HIV-1 infection with early antiretroviral therapy.
The early initiation of antiretroviral therapy reduced rates of sexual transmission of HIV-1 and clinical events, indicating both personal and public health benefits from such therapy.
Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
The isolation of a T-cell tropic retrovirus from three immunodeficient macaques and one macaque with lymphoma is described, and it is indicated that it is related to the causative agent of acquired immune deficiency syndrome in humans.
Antiretroviral Therapy for the Prevention of HIV-1 Transmission.
The early initiation of ART led to a sustained decrease in genetically linked HIV-1 infections in sexual partners, and was associated with a 93% lower risk of linked partner infection than was delayed ART.
Antiretroviral regimens in pregnancy and breast-feeding in Botswana.
All regimens of HAART from pregnancy through 6 months post partum resulted in high rates of virologic suppression, with an overall rate of mother-to-child transmission of 1.1%.
Response to antiretroviral therapy after a single, peripartum dose of nevirapine.
- S. Lockman, R. Shapiro, M. Essex
- Medicine, PsychologyThe New England journal of medicine
- 11 January 2007
Women who received a single dose of nevirapine to prevent perinatal transmission of HIV-1 had higher rates of virologic failure with subsequent ne virapine-based antiretroviral therapy than did women without previous exposure to nevirAPine.
Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana.
HAART receipt during pregnancy was associated with increased PTD, SGA, and SB, and low CD4(+) was independently associated with SB and S GA, and maternal hypertension during pregnancy with PTD and SGA.
A randomized trial of multivitamin supplements and HIV disease progression and mortality.
Multivitamin supplements delay the progression of HIV disease and provide an effective, low-cost means of delaying the initiation of antiretroviral therapy in HIV-infected women.
SEROLOGICAL EVIDENCE FOR VIRUS RELATED TO SIMIAN T-LYMPHOTROPIC RETROVIRUS III IN RESIDENTS OF WEST AFRICA
Estimating the lost benefits of antiretroviral drug use in South Africa.
- P. Chigwedere, G. Seage, S. Gruskin, Tun‐Hou Lee, M. Essex
- Medicine, PsychologyJournal of acquired immune deficiency syndromes
- 1 December 2008
Using modeling, this work compared the number of persons who received ARVs for treatment and prevention of mother-to-child HIV transmission between 2000 and 2005 with an alternative of what was reasonably feasible in the country during that period.