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Barriers to Antiretroviral Adherence for Patients Living with HIV Infection and AIDS in Botswana
Background: Botswana has the highest rate of HIV infection in the world, estimated at 36% among the population aged 15‐49 years. To improve antiretroviral (ARV) treatment delivery, we conducted aExpand
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Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
The isolation of a T-cell tropic retrovirus from three immunodeficient macaques and one macaque with lymphoma is described. The morphology, growth characteristics, and antigenic properties of thisExpand
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Antiretroviral regimens in pregnancy and breast-feeding in Botswana.
BACKGROUND The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy duringExpand
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Response to antiretroviral therapy after a single, peripartum dose of nevirapine.
BACKGROUND A single dose of nevirapine during labor reduces perinatal transmission of human immunodeficiency virus type 1 (HIV-1) but often leads to viral nevirapine resistance mutations in mothersExpand
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Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana.
BACKGROUND It is unknown whether adverse birth outcomes are associated with maternal highly active antiretroviral therapy (HAART) in pregnancy, particularly in resource-limited settings. METHODS WeExpand
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A randomized trial of multivitamin supplements and HIV disease progression and mortality.
BACKGROUND Results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (HIV) disease. METHODS We enrolled 1078 pregnantExpand
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Antiretroviral Therapy for the Prevention of HIV-1 Transmission.
BACKGROUND An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections causedExpand
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Male circumcision: an acceptable strategy for HIV prevention in Botswana
Background: Male circumcision is known to reduce the risk of acquiring HIV, but few studies have been performed to assess its acceptability among either children or adults in sub-Saharan Africa.Expand
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Serological evidence is presented here suggesting that a virus closely related to simian T-lymphotropic virus type III (STLV-III) infects man in Senegal, west Africa, a region where AIDS orExpand
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Prevention of HIV-1 infection with early antiretroviral therapy.
BACKGROUND Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS In nine countries, weExpand
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