Gene Knockdown Techniques

Known as: Knock-Downs, Gene, Techniques, Gene Knockdown, Technique, Gene Knock-Down 
The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
DROSHA is a nuclear RNase III enzyme responsible for cleaving primary microRNAs (miRNAs) into precursor miRNAs and thus is… (More)
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Highly Cited
2010
Highly Cited
2010
RNA interference (RNAi) is a powerful strategy for gene function study in insects. Here, we described the development of a RNAi… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND RNA interference (RNAi) is a powerful method to inhibit gene expression in a sequence specific manner. RESULTS Here… (More)
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Highly Cited
2007
Highly Cited
2007
During neuronal activity, extracellular potassium concentration ([K+]out) becomes elevated and, if uncorrected, causes neuronal… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Grasshopper serves as important model system in neuroscience, development and evolution. Representatives of this… (More)
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Highly Cited
2005
Highly Cited
2005
N-methyl-D-aspartate (NMDA) receptor activation, at the level of the spinal cord, has been shown to play an important role in the… (More)
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Highly Cited
2004
Highly Cited
2004
Gene expression analysis implicates an increasing number of novel genes in the brain as potential targets for the treatment of… (More)
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Highly Cited
2003
Highly Cited
2003
We describe the use of lentiviral vectors expressing small interfering RNAs (siRNAs) to knock down the expression of specific… (More)
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Highly Cited
2003
Highly Cited
2003
Conditional mutant techniques that allow spatial and temporal control over gene expression can be used to create mice with… (More)
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